Fig. 2

ROC curve of four tumor markers for HCC. a shows the ROC curve of Hsp90α, AFP, CEA, and CA-199 alone in HCC patients. b shows the ROC curve of the combined application of any two of the four biomarkers Hsp90α, AFP, CEA, and CA-199 in HCC patients. c shows the ROC curve of the combination of any three of the four biomarkers Hsp90α, AFP, CEA, and CA-199 in HCC patients. ROC, receiver operating characteristic; HCC, hepatocellular carcinoma; SEN, sensitivity; SPE, specificity; Hsp90α, plasma heat shock protein 90 alpha; AFP, alpha-fetoprotein; CEA, carcinoembryonic antigen; CA199, carbohydrate antigen199