From: Clinical significance of circulating tumour cells and Ki-67 in renal cell carcinoma
Before surgery | CTC counts, n | P value | CTCs, n (%) | P value | |||
< 5 (n = 17) | ≥5 (n = 24) |  | Negative (n = 7) | Positive (n = 34) |  | ||
  Ki-67 index | < 10 (n = 26) | 15 | 11 | 0.012* | 7(26.9) | 19(73.1) | 0.114 |
 | 10–20 (n = 8) | 2 | 6 |  | 0(0.0) | 8(100.0) |  |
 | 21–40 (n = 7) | 0 | 7 |  | 0(0.0) | 7(100.0) |  |
 | Low proliferation (n = 26) | 15 | 11 | 0.005* | 7(26.9) | 19(73.1) | 0.035* |
 | High proliferation (n = 15) | 2 | 13 |  | 0(0.0) | 15(100.0) |  |
Immediately after surgery | CTC counts, n | P value | CTCs, n (%) | P value | |||
< 5 (n = 18) | ≥ 5 (n = 23) |  | Negative (n = 6) | Positive (n = 35) |  | ||
  Ki-67 index | < 10 (n = 26) | 14 | 12 | 0.288 | 5 (19.2) | 21 (80.8) | 0.583 |
 | 10–20 (n = 8) | 2 | 6 |  | 0 (0.0) | 8 (100.0) |  |
 | 21–40 (n = 7) | 2 | 5 |  | 1 (14.3) | 6 (85.7) |  |
 | Low proliferation (n = 26) | 14 | 12 | 0.091 | 5 (19.2) | 21 (80.8) | 0.388 |
 | High proliferation (n = 15) | 4 | 11 |  | 1 (6.67) | 14 (93.3) |  |
One week after surgery | CTC counts, n | P value | CTCs, n (%) | P value | |||
< 5 (n = 28) | ≥ 5 (n = 13) |  | Negative (n = 11) | Positive (n = 30) |  | ||
  Ki-67 index | < 10 (n = 26) | 21 | 5 | 0.028* | 7 (26.9) | 19 (73.1) | 0.612 |
 | 10–20 (n = 8) | 5 | 3 |  | 3 (37.5) | 5 (62.5) |  |
 | 21–40 (n = 7) | 2 | 5 |  | 1 (14.3) | 6 (85.7) |  |
 | Low proliferation (n = 26) | 21 | 5 | 0.038* | 7 (26.9) | 19 (73.1) | 0.719 |
 | High proliferation (n = 15) | 7 | 8 |  | 4 (26.7) | 11 (73.3) |  |