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Table 5 The correlation between CTC counts and the Ki-67 index during the perioperative period

From: Clinical significance of circulating tumour cells and Ki-67 in renal cell carcinoma

Before surgery

CTC counts, n

P value

CTCs, n (%)

P value

< 5 (n = 17)

≥5 (n = 24)

 

Negative (n = 7)

Positive (n = 34)

 

  Ki-67 index

< 10 (n = 26)

15

11

0.012*

7(26.9)

19(73.1)

0.114

 

10–20 (n = 8)

2

6

 

0(0.0)

8(100.0)

 
 

21–40 (n = 7)

0

7

 

0(0.0)

7(100.0)

 
 

Low proliferation (n = 26)

15

11

0.005*

7(26.9)

19(73.1)

0.035*

 

High proliferation (n = 15)

2

13

 

0(0.0)

15(100.0)

 

Immediately after surgery

CTC counts, n

P value

CTCs, n (%)

P value

< 5 (n = 18)

≥ 5 (n = 23)

 

Negative (n = 6)

Positive (n = 35)

 

  Ki-67 index

< 10 (n = 26)

14

12

0.288

5 (19.2)

21 (80.8)

0.583

 

10–20 (n = 8)

2

6

 

0 (0.0)

8 (100.0)

 
 

21–40 (n = 7)

2

5

 

1 (14.3)

6 (85.7)

 
 

Low proliferation (n = 26)

14

12

0.091

5 (19.2)

21 (80.8)

0.388

 

High proliferation (n = 15)

4

11

 

1 (6.67)

14 (93.3)

 

One week after surgery

CTC counts, n

P value

CTCs, n (%)

P value

< 5 (n = 28)

≥ 5 (n = 13)

 

Negative (n = 11)

Positive (n = 30)

 

  Ki-67 index

< 10 (n = 26)

21

5

0.028*

7 (26.9)

19 (73.1)

0.612

 

10–20 (n = 8)

5

3

 

3 (37.5)

5 (62.5)

 
 

21–40 (n = 7)

2

5

 

1 (14.3)

6 (85.7)

 
 

Low proliferation (n = 26)

21

5

0.038*

7 (26.9)

19 (73.1)

0.719

 

High proliferation (n = 15)

7

8

 

4 (26.7)

11 (73.3)

 
  1. *P < 0.05, the difference was statistically significant