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Table 1 Clinical characteristics of the patients with the low-risk group and high-risk group

From: CT imaging-based machine learning model: a potential modality for predicting low-risk and high-risk groups of thymoma: “Impact of surgical modality choice”

Patients (n = 83)

Low-risk group, n (%)

51 (61)

High-risk group, n (%)

32 (39)

p-value*

Sex, n (%)

 Male

25 (49)

20 (62)

0.23

 Female

26 (51)

12 (38)

Age, median (range) (years)

50 (21–73)

50 (24–66)

0.68

Smoking status, n (%)

 Never

34 (67)

18 (56)

0.34

 Current or past smoker

17 (33)

14 (44)

Previous malignancy or synchronous tumor, n (%)

 Absent

48 (94)

27 (52)

0.25

 Present

3 (6)

5 (48)

Clinical presentation, n (%)

 Asymptomatic

16 (31)

10 (31)

0.99

 Symptomatic

35 (69)

22 (69)

Myasthenia gravis, n (%)

 Absent

43 (84)

22 (69)

0.09

 Present

8 (16)

10 (31)

LDH, median (range) (U/L)

180 (113–338)

179 (89–310)

0.80

ALP, median (range) (U/L)

68 (29–124)

67 (31–167)

0.74

CRP, median (range) (mg/L)

4.1 (0.6–70.7)

3.5 (0.1–25.8)

0.67

HGB, median (range) (g/dL)

14 (9–16.6)

13.6 (9–16.3)

0.62

WBC count, median (range) (×109/L)

7.7 (3.3–16.8)

7.3 (3.9–13.9)

0.97

LYMP count, median (range) (×109/L)

2.1 (0.01–6.1)

1.8 (0.5–3.8)

0.10

PLT count, median (range) (×109/L)

258 (121–454)

233 (122–404)

0.58

Type of treatment, n (%)

 Surgery±adjuvant treatment

44 (86)

28 (87)

1.00

 Definitive chemotherapy±radiotherapy

7 (14)

4 (13)

Largest dimension of tumor size on CT (mean ± SD) (range) in mm

66.8± 2.1 (21–160)

63±2.2 (20–134)

0.55

  1. LDH lactate dehydrogenase, ALP alkaline phosphatase, CRP C-reactive protein, HGB hemoglobin, WBC white blood cell, LYMP lmyphocyte, PLT platelet
  2. *Differences were compared using the t-test/Mann-Whitney U test, Pearson Chi-square test/Fisher’s exact test