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Table 4 Univariate and Multivariable Cox Regression Analysis for Overall Survival

From: Neoadjuvant chemotherapy followed by hyperthermic intraperitoneal chemotherapy for patients with colorectal peritoneal metastasis: a retrospective study of its safety and efficacy

Variable Overall survival
Univariate analysis Multivariate analysis
HR (95%CI) P HR (95%CI) P
Gender: female/male 1.13 (0.53–2.43) 0.753   
Age at operation (≥ 65 years/< 65 years) 2.12 (0.98–4.60) 0.056   
Preoperative chemotherapy (yes/no) 0.36 (0.13–0.92) 0.033 0.55 (0.22–1.39) 0.204
T stage (T4/T3) 1.61 (0.73–3.54) 0.235   
N stage     
 N0 Reference Reference   
 N1 1.29 (0.57–2.94) 0.545   
 N2 2.26 (0.71–7.16) 0.167   
Site of original (rectum/colon) 1.48 (0.63–3.51) 0.373   
Histology (mucinous/adenocarcinoma) 2.05 (0.96–4.40) 0.065   
Preoperative CEA level (≥ 5 ng/ml/< 5 ng/ml) 1.68 (0.78–3.58) 0.183   
Liver metastases (yes/no) 1.24 (0.50–3.08) 0.648   
HIPEC regimen (lobaplatin/non-lobaplatin) 1.38 (0.62–3.05) 0.427   
Presence of ascites (yes/no) 1.20 (0.55–2.60) 0.650   
PCI score (≥ 12/< 12) 2.98 (1.41–6.32) 0.004 1.49 (0.61–3.66) 0.381
CC score (2–3/0–1) 4.20 (1.89–9.36) < 0.001 2.99 (1.14–7.84) 0.026
Grade 3–4 postoperative complication (yes/no) 1.62 (0.74–3.57) 0.229