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Table 3 Surgical outcomes and postoperative courses of the 52 enrolled patients

From: Neoadjuvant chemotherapy followed by hyperthermic intraperitoneal chemotherapy for patients with colorectal peritoneal metastasis: a retrospective study of its safety and efficacy

Variable All patients (n = 52) NAC (n = 20) Non-NAC (n = 32) P
Operative time (min, mean ± SD) 276.3 ± 60.1 245.5 ± 59.1 289.4 ± 63.4 0.082
Intraoperative blood loss (mL, mean ± SD) 104.3± 111.1 115.0 ± 111.3 100.8 ± 111.0 0.661
Postoperative complication (Grades 3–4) 18 (34.6) 8 (40.0) 10 (31.3) 0.519
 Arrhythmia 1 (1.9) 1 (5.0) 0 (0)  
 Pneumonia 3 (5.8) 2 (10.0) 1 (3.1)  
 Anastomotic leakage 3 (5.8) 1 (5.0) 2 (6.3)  
 Ileus 7 (13.5) 3 (15.0) 4 (12.5)  
 Abdominal abscess 3 (5.8) 1 (5.0) 2 (6.3)  
 Intra-abdominal haemorrhage 1 (1.9) 0 (0) 1 (3.1)  
 Wound infection 5 (9.6) 2 (10.0) 3 (9.4)  
Toxicity indexes after HIPEC 22 (42.3) 10 (50.0) 12 (37.5) 0.375
 Abnormal changes in neutrophils 6 (11.5) 3 (15.0) 3 (9.4) 0.864
 Abnormal changes in platelets 8 (15.4) 6 (30.0) 2 (6.3) 0.043
 Abnormal changes in ALT 8 (15.4) 2 (10.0) 6 (18.8) 0.463
 Abnormal changes in creatinine 3 (5.8) 1 (5.0) 2 (6.3) 1.000
Time to first flatus (day, mean ± SD) 3.8 ± 1.8 4.1 ± 1.9 3.6 ± 1.8 0.811
Total hospital stay (day, mean ± SD) 14.4 ± 5.0 15.4 ± 6.0 13.9 ± 3.9 0.333
Re-operation 1 (1.9) 1 (5.0) 0 (0) 1.000
Mortality (%) 0 (0) 0 (0) 0 (0) 1.000