Table 3 Surgical outcomes and postoperative courses of the 52 enrolled patients
Variable | All patients (n = 52) | NAC (n = 20) | Non-NAC (n = 32) | P |
|---|---|---|---|---|
Operative time (min, mean ± SD) | 276.3 ± 60.1 | 245.5 ± 59.1 | 289.4 ± 63.4 | 0.082 |
Intraoperative blood loss (mL, mean ± SD) | 104.3± 111.1 | 115.0 ± 111.3 | 100.8 ± 111.0 | 0.661 |
Postoperative complication (Grades 3–4) | 18 (34.6) | 8 (40.0) | 10 (31.3) | 0.519 |
 Arrhythmia | 1 (1.9) | 1 (5.0) | 0 (0) |  |
 Pneumonia | 3 (5.8) | 2 (10.0) | 1 (3.1) |  |
 Anastomotic leakage | 3 (5.8) | 1 (5.0) | 2 (6.3) |  |
 Ileus | 7 (13.5) | 3 (15.0) | 4 (12.5) |  |
 Abdominal abscess | 3 (5.8) | 1 (5.0) | 2 (6.3) |  |
 Intra-abdominal haemorrhage | 1 (1.9) | 0 (0) | 1 (3.1) |  |
 Wound infection | 5 (9.6) | 2 (10.0) | 3 (9.4) |  |
Toxicity indexes after HIPEC | 22 (42.3) | 10 (50.0) | 12 (37.5) | 0.375 |
 Abnormal changes in neutrophils | 6 (11.5) | 3 (15.0) | 3 (9.4) | 0.864 |
 Abnormal changes in platelets | 8 (15.4) | 6 (30.0) | 2 (6.3) | 0.043 |
 Abnormal changes in ALT | 8 (15.4) | 2 (10.0) | 6 (18.8) | 0.463 |
 Abnormal changes in creatinine | 3 (5.8) | 1 (5.0) | 2 (6.3) | 1.000 |
Time to first flatus (day, mean ± SD) | 3.8 ± 1.8 | 4.1 ± 1.9 | 3.6 ± 1.8 | 0.811 |
Total hospital stay (day, mean ± SD) | 14.4 ± 5.0 | 15.4 ± 6.0 | 13.9 ± 3.9 | 0.333 |
Re-operation | 1 (1.9) | 1 (5.0) | 0 (0) | 1.000 |
Mortality (%) | 0 (0) | 0 (0) | 0 (0) | 1.000 |