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Table 2 Univariate analysis of risk factors for CLNM among PTC patients

From: Risk factors for central lymph node metastasis in the cervical region in papillary thyroid carcinoma: a retrospective study

Factors

CLNM– group (n=1604)

CLNM+ group (n=982)

P values

Sex

  

<0.001

 Male

284 (17.7%)

281 (28.6%)

 

 Female

1320 (82.3%)

701 (71.4%)

 

Age (years)

44.89±10.60

39.94±10.45

<0.001

TD (cm)

  

<0.001

 ≤1 (T1a)

1308 (81.5%)

614 (62.5%)

 

 >1 to ≤2 (T1b)

245 (15.3%)

289 (29.4%)

 

 >2 < to ≤4 (T2)

49 (3.1%)

73 (7.4%)

 

 >4 (T3)

2 (0.1%)

6 (0.6%)

 

Tumor mulifocality

  

<0.001

 Single-focal

1025 (63.9%)

551 (56.1%)

 

 Multifocal

579 (36.1%)

431 (43.9%)

 

Capsular invasion

  

0.010

 Yes

158 (9.9%)

129 (13.1%)

 

 No

1446 (90.1%)

853 (86.9%)

 

Nerve invasion

  

0.228

 Yes

38 (2.4%)

31 (3.2%)

 

 No

1566 (97.6%)

951 (96.8%)

 

Vascular invasion

  

<0.001

 Yes

25 (1.6%)

85 (8.7%)

 

 No

1582 (98.6%)

897 (91.3%)

 

Number of lymph nodes in central region

8.37±5.52

10.65±6.12

<0.001

Thyroid function (uIU/ML)

   

 TSH

2.40±1.04

2.40±1.00

0.967

 TgAb

69.21±112.28

69.92±115.80

0.768

 TPOAb

204.36±401.47

189.89±387.40

0.084

  1. P values for comparisons of CLMN– and CLMN+ groups
  2. Abbreviations: CLNM central lymph node metastasis, TD tumor diameter, TSH thyroid-stimulating hormone, TgAb thyroglobulin antibody, TPOAb thyroid peroxidase antibody