Clinical/oncological outcomes | No. of studies | SEA | CJP | Effect estimate | Heterogeneity | ||||
---|---|---|---|---|---|---|---|---|---|
Events | Total | Events | Total | RR/WMD (95% CI) | P | I2 | P | ||
Anastomotic leakage | 7 [31–36, 39, 40] | 20 | 279 | 33 | 281 | 0.68 (0.41, 1.13) | 0.14 | 0% | 0.42 |
Anastomotic stricture | 3 [32, 34, 41] | 4 | 165 | 4 | 158 | 0.97 (0.29, 3.25) | 0.96 | 0% | 0.19 |
Pouch-related complications | 4 [31, 34, 36, 41] | 1 | 188 | 4 | 187 | 0.50 (0.13, 1.96) | 0.32 | 0% | 0.63 |
Pelvic sepsis | 4 [31, 32, 36, 38] | 17 | 151 | 10 | 158 | 1.77 (0.87, 3.59) | 0.11 | 0% | 0.84 |
Intestinal obstruction | 4 [32, 36, 38, 41] | 13 | 208 | 13 | 209 | 1.08 (0.53, 2.24) | 0.83 | 0% | 0.43 |
Wound infection | 4 [32, 36, 38, 41] | 6 | 208 | 5 | 209 | 1.18 (0.39, 3.62) | 0.77 | 0% | 0.84 |
Rectovaginal fistula | 3 [31, 34, 41] | 3 | 145 | 3 | 137 | 0.95 (0.24, 3.79) | 0.94 | 0% | 0.42 |
Urinary complications | 3 [32, 34, 36] | 8 | 121 | 12 | 128 | 0.72 (0.31, 1.69) | 0.45 | 0% | 0.53 |
Cardiovascular complications | 2 [32, 36] | 3 | 93 | 2 | 100 | 1.55 (0.31, 7.76) | 0.59 | 0% | 0.62 |
Pneumonia | 2 [32, 36] | 2 | 93 | 3 | 100 | 0.79 (0.16, 3.85) | 0.77 | 0% | 0.51 |
Mortality (in-hospital/< 30days) | 3 [32, 36, 41] | 5 | 189 | 3 | 185 | 1.53 (0.43, 5.45) | 0.51 | 39% | 0.20 |
Reoperations (except stoma reversal) | 3 [32, 36, 38] | 17 | 130 | 25 | 134 | 0.74 (0.36, 1.52) | 0.41 | 24.7% | 0.27 |
Relapse (< 2 year) | 2 [36, 38] | 4 | 80 | 4 | 84 | 1.05 (0.27, 4.03) | 0.947 | 0% | 0.99 |
Postoperative hospital stay (day) | 4 [32, 36, 38, 39] | - | 160 | - | 156 | 0.42 (− 1.72, 2.56) | 0.70 | 30.5% | 0.23 |