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Table 1 Basic characteristics between patients receiving UFT or S-1 as adjuvant chemotherapy

From: Adjuvant tegafur-uracil (UFT) or S-1 monotherapy for advanced gastric cancer: a single center experience

 

All

(n = 86)

UFT

(n = 37)

S-1

(n = 49)

p value

Sex (male)

56

(65.1)

25

(67.6)

31

(63.3)

0.85

Age (years old)

57.5

± 12.2

59.1

± 13.9

56.3

± 10.7

0.31

Operative method

      

0.10

 Distal gastrectomy

65

(75.6)

26

(70.3)

39

(79.6)

 

 Total gastrectomy

18

(20.9)

11

(29.7)

7

(14.3)

 

 Proximal gastrectomy

3

(3.5)

0

(0)

3

(6.1)

 

Site

      

0.33

 Antrum and low body

61

(70.9)

26

(70.3)

35

(71.4)

 

 Middle and high body

18

(20.9)

9

(24.3)

9

(18.4)

 

 Whole stomach

1

(1.2)

1

(2.7)

0

(0)

 

 Remnant

6

(7.0)

1

(2.7)

5

(10.2)

 

Size (cm)

4.4

± 2.0

4.3

± 2.0

4.6

± 2.1

0.49

Bormann type

      

0.047*

 I or II

21

(24.4)

5

(13.5)

16

(32.7)

 

 III or IV

65

(75.6)

32

(86.5)

33

(67.3)

 

Lauren classification

      

0.49

 Intestinal type

31

(36.0)

13

(35.1)

18

(36.7)

 

 Diffuse type

39

(45.3)

19

(51.4)

20

(40.8)

 

 Mixed type

16

(18.6)

5

(13.5)

11

(22.4)

 

Cell differentiation

      

0.54

 Well-differentiated

7

(8.2)

4

(11.1)

3

(6.1)

 

 Moderately differentiated

23

(27.1)

11

(30.6)

12

(24.5)

 

 Poorly- or un-differentiated

55

(64.7)

21

(58.3)

34

(69.4)

 

LN metastasis (number)

4.5

± 5.7

5.2

± 7.8

3.9

± 3.3

0.35

LN harvested (number)

34.9

± 18.6

33.9

± 19.3

35.6

± 18.2

0.67

Lymphovascular invasion

56

(65.1)

25

(67.6)

31

(63.3)

0.85

Perineural invasion

57

(66.3)

25

(67.6)

32

(65.3)

0.99

T stage (AJCC 8th)

      

<0.001*

 1

0

(0)

0

(0)

0

(0)

 

 2

19

(21.8)

8

(21.6)

11

(22.4)

 

 3

42

(48.3)

8

(21.6)

33

(67.3)

 

 4

26

(29.9)

21

(56.8)

5

(10.2)

 

N stage (AJCC 8th)

      

0.48

 0

2

(2.3)

0

(0)

2

(4.1)

 

 1

33

(38.4)

15

(40.5)

18

(36.7)

 

 2

36

(41.9)

14

(37.8)

22

(44.9)

 

 3

15

(17.4)

8

(21.6)

7

(14.3)

 

Pathological stage (AJCC 8th)

      

0.23

 II

33

(38.4)

11

(29.7)

22

(44.9)

 

 III

53

(61.6)

26

(70.3)

27

(55.1)

 

Follow-up (months)

52.6

± 31.2

65.9

± 36.9

43.3

± 22.6

0.003*

  1. Data are mean ± SD or n (%)
  2. UFT tegafur-uracil, S-1 tegafur-gimeracil-oteracil, LN lymph node, AJCC American Joint Cancer Committee
  3. *p value < 0.05 after comparing between the UFT and S-1 groups