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Fig. 5 | World Journal of Surgical Oncology

Fig. 5

From: MicroRNA-490-3p inhibits migration and chemoresistance of colorectal cancer cells via targeting TNKS2

Fig. 5

TNKS2 was the downstream target of miR-490-3p. a The wild-type and mutant plasmids of the TNKS2 mRNA 3′UTR were constructed according to the potential binding sites of the miR-490-3p and TNKS2 mRNA. b, c The binding of miR-490-3p and mRNA 3′UTR of wild-type TNKS2 was verified by luciferase assay. d TNKS2 siRNA sequences were used to establish the knockdown model of TNKS2

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