Fig. 4
miR-490-3p was negatively correlated with the expression of TNKS2. a A total of 16 genes were screened using DIANA, TargetScan, and miRDB databases. b The relative mRNA expression of TNKS2 exhibited negative correlation with miR-490-3p (p< 0.05). c The relative RBM12 mRNA level exhibited no correlation with miR-490-3p (p> 0.05). d The relative ZC3H6 mRNA level exhibited no correlation with miR-490-3p (p> 0.05). e The relative CLOCK mRNA level exhibited no correlation with miR-490-3p (p> 0.05). f The relative PCBP1 mRNA level exhibited no correlation with miR-490-3p (p> 0.05). g The relative RASAL2 mRNA level exhibited no correlation with miR-490-3p (p> 0.05). h TNKS2 protein expression was measured. i TNKS2 was significantly inhibited in the miR-490-3p overexpressed cell line but increased in the miR-490-3p knockdown cell line (p< 0.001)