Fig. 1

Significant low expression of miR-490-3p expression in colorectal cancer tissues and cell lines. a The expression of miR-490-3p was significantly decreased in 162 colorectal cancer samples (p<0.001). b Low expression in 150 tumor tissues and high expression in 12 tumor tissues. c miR-490-3p expression was lower in tissues with lymph node metastasis (p<0.001). d miR-490-3p expression in tissues with distant metastasis was lower than that without distant metastasis (p<0.001). e Significant low expression of miR-490-3p expression in colorectal cancer cell lines (p<0.001); f miR-490-3p expression was significantly higher in tissues of Dukes stages compared with Dukes (p<0.001); g miR-490-3p expression was significantly higher in the well or moderately differentiated tissues compared with poorly differentiated tissues (p<0.001); h miR-490-3p expression was significantly higher in the primary tumor tissues compared with lymph nodes or metastatic lesions (p<0.05)