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Table 4 Comparison of the performance of the 8th edition of the TNM Staging System alone and the 8th edition of the TNM Staging System combined with LVI. We combined the LVI with the 8th TNM staging system. A comparison was made to estimate the prognostic value between the new system and the 8th TNM staging system. As listed in Table 4, the 8th TNM staging system combined with LVI had a higher C-index than the 8th TNM staging system alone (C-index, 0.895 vs. 0.833), which indicates a better prognostic value for CRC patients

From: Prognostic value of lymphovascular invasion in stage II colorectal cancer patients with an inadequate examination of lymph nodes

Classification

Stage

n

5-year OS (%)

C-index

95% CI

8th TNM

I

173

90.2

0.833

0.785–0.889

II

409

72.5

III

838

56.2

8th TNM+LVI

I

173

90.2

0.895

0.812–0.924

II

361

74.2

III

886

56.9

  1. C-index Harrell’s concordance index; LVI Lymphovascular invasion; OS Overall survival; CI Confidence interval