Table 1 Clinicopathologic characteristics of CRC patients. One thousand four hundred and twenty CRC patients from February 2007 to February 2013 who met the inclusion criteria were analyzed in this study. The clinicopathologic characteristics of 1420 CRC patients and the 409 stage II patients are listed in Table 1. Of the 409 stage II patients, 145 patients (35.5%) were LVI+ and 264 (64.5%) were LVI−
Parameters | Overall patients | Stage II patients |
|---|---|---|
| Â | n (%) | n (%) |
Sex | ||
 Female | 598 (42.1) | 169 (41.3) |
 Male | 822 (57.9) | 240 (58.7) |
Age (years) | ||
 ≤65 | 669 (47.1) | 198 (48.4) |
 >65 | 751 (52.9) | 211 (51.6) |
Tumor site | ||
 Colon | 846 (59.6) | 217 (53.1) |
 Rectum | 574 (40.4) | 192 (46.9) |
Tumor size (cm) | Â | Â |
 ≤4 | 688 (48.5) | 209 (51.1) |
 >4 | 732 (51.5) | 200 (48.9) |
Lymphovascular invasion | ||
 Positive | 486 (34.2) | 145 (35.5) |
 Negative | 934 (65.8) | 264 (64.5) |
T-stage | Â | Â |
 T1 | 233 (16.4) |  |
 T2 | 393 (27.7) |  |
 T3 | 457 (32.2) | 218 (53.3) |
 T4 | 337 (23.7) | 191 (46.7) |
N-stage | ||
 N0 | 582 (41.0) | 409 (100.0) |
 N1 | 498 (35.1) |  |
 N2 | 340 (23.9) |  |
Differentiation degree | ||
 Well | 666 (46.9) | 198 (48.4) |
 Moderate | 582 (41.0) | 182 (44.5) |
 Poor | 172 (12.1) | 29 (7.1) |
CEA | ||
 ≤5ng/ml | 836 (58.9) | 243 (59.4) |
 >5ng/ml | 584 (41.1) | 166 (40.6) |
CA19-9 | ||
 ≤37U/ml | 1106 (77.9) | 322 (78.7) |
 >37U/ml | 314 (22.1) | 87 (21.3) |
Retrieved LN | Â | Â |
 <12 | 564 (39.7) | 164 (40.1) |
 ≥12 | 856 (60.3) | 245 (59.9) |
Treatment | ||
 ACT | 960 (67.6) | 265 (64.8) |
 SA | 460 (32.4) | 144 (35.2) |
TNM stage | ||
 I | 173 (12.2) |  |
 II | 409 (28.8) |  |
  IIA | 174 (12.3) |  |
  IIB | 121 (8.5) |  |
  IIC | 114 (8.0) |  |
 III | 838 (59.0) |  |
  IIIA | 324 (22.8) |  |
  IIIB | 287 (20.2) |  |
  IIIC | 227 (16.0) |  |
KRAS status | ||
 Wild type | 975 (68.7) | 248 (60.6) |
 Mutant type | 445 (31.3) | 161 (39.4) |
PNI | Â | Â |
 Positive | 276 (19.4) | 90 (22.0) |
 Negative | 1144 (80.6) | 319 (78.0) |
TB | ||
 Low | 995 (70.1) | 294 (71.9) |
 High | 425 (29.9) | 115 (28.1) |