Variable | 279 patients (% or [Q1 − Q3] †) | |
---|---|---|
No recurrence (n=260, %) | Recurrence (n=19, %) | |
Age | 63.8± 12.4 | 58.4 ± 11.0 |
BMI (kg/m2) | 24.1± 3.2 | 24.8 ± 3.4 |
Male gender | 141 (54.2) | 12 (63.2) |
Family cancer history | 79 (30.4) | 8 (42.1) |
Preoperative CEA (ng/mL) | 1.8 [1.1–2.7] † | 2.3 [1.5–6.7] † |
Preoperative CEA ≥ 5* | 30 (11.5) | 7 (36.8) |
Preoperative hemoglobin (g/dL) | 12.8 ± 2.0 | 13.8 ± 1.8 |
Preoperative albumin (g/dL) | 4.23 ± 0.40 | 4.32 ± 0.37 |
Distance from anal verge (cm)* | 5.9 ± 1.7 | 4.9 ± 1.9 |
Distance from anal verge ≤ 5 | 108 (41.5) | 12 (63.2) |
Operation type | ||
Low anterior resection | 241 (92.7) | 17 (89.5) |
Abdomino-perineal resection | 17 (6.5) | 2 (10.5) |
Hartmann’s procedure | 2 (0.8) | 0 |
Neo-adjuvant radiotherapy ‡ | 41 (15.8) | 6 (31.6) |
Adjuvant therapy | 4 (1.5) | 0 |
Chemotherapy | 3 (1.2) | 0 |
CRT | 1 (0.4) | 0 |
PeriOP colostomy/ileostomy | 149 (57.3) | 15 (78.9) |
PostOP complication/morbidity | 68 (26.2) | 3 (15.8) |
Early | 43 (16.5) | 3 (15.8) |
Late | 37 (14.2) | 1 (5.3) |
Resection margin (cm) | 1.5 [0.8–2.2] † | 0.8 [0.5–1.7] † |
Resection margin < 0.9 * | 78 (30.0) | 10 (52.6) |
Resection margin < 1.4 * | 118 (45.4) | 14 (73.7) |
Tumor diameter (cm) | 3.0 ± 1.4 | 3.3 ± 1.1 |
Tumor diameter ≥ 2.7 | 137 (52.7) | 13 (72.2) |
T stage | ||
T1 | 98 (37.7) | 5 (26.3) |
T2 | 162 (62.3) | 14 (73.7) |
Lymph node yield | 20 [14–28] † | 16 [11–33] † |
Lymph node yield ≥ 14* | 207 (79.6) | 11 (57.9) |
Lymphovascular invasion | 12 (4.6) | 1 (5.3) |
Perineural invasion | 13 (5.0) | 0 |
Differentiation | ||
Poor | 4 (1.5) | 1 (5.3) |
Moderate | 195 (75.0) | 15 (78.9) |
Well | 61 (23.5) | 3 (15.8) |
Follow-up (month) | 73.5 [48–108] † | |
Total follow-up length | 79.6 [51–109] † | 64.9 [54–102] † |
Time to local recurrence | 25.6 [13.7–38.8] † | |
Time to distant metastasis | 31.4 [12.9–59.2] † |