Univariate analysis | Multivariate analysis | ||||||
---|---|---|---|---|---|---|---|
Factors | n/n | 5-year survival (%) | p value | Factors | Hazard ratio | 95% C.I. | p value |
Curability (A, B/C) | 43/9 | 32.3/0.00 | 0.003 | Curability (A, B/C) | 1.634 | 0.566–4.306 | 0.348 |
T (1, 2/3, 4) | 18/34 | 57.0/10.4 | < 0.001 | T (1, 2/3, 4) | 2.847 | 0.944–9.313 | 0.064 |
N (0/1–3) | 36/16 | 36.5/6.73 | 0.001 | N (0/1–3) | 3.091 | 1.348–7.002 | 0.008 |
cStage (I, II/III, IV) | 15/37 | 61.9/13.0 | < 0.001 | Â | Â | Â | Â |
Tumor type (MF/MF + PI) | 20/32 | 38.6/19.2 | 0.163 | Â | Â | Â | Â |
Tumor location (grossly peripheral/perihilar) | 47/5 | 27.7/20.0 | 0.667 | Â | Â | Â | Â |
Differentiation (Cholangiolo/tub1/others) | 6/14/32 | 40.0/17.9/30.8 | 0.235 | Â | Â | Â | Â |
SSTR2†, Bcl2‡ expression (p-Group H + U/p-Group P) | 38/14 | 22.6/39.3 | 0.046 | SSTR2, Bcl2 (p-Group H + U/p-Group P) | 1.055 | 0.370–2.880 | 0.917 |
Tumor thrombus in the portal vein (−/+) | 33/19 | 35.7/9.40 | 0.001 | Tumor thrombus in the portal vein (−/+) | 2.237 | 0.963–5.383 | 0.061 |
Tumor thrombus in the hepatic vein (−/+) | 45/7 | 25.9/28.6 | 0.660 | Intrahepatic metastasis (−/+) | 2.049 | 0.712–5.474 | 0.176 |
Intrahepatic metastasis (−/+) | 44/8 | 30.3/12.5 | 0.030 |  |  |  |  |
CA19-9§ (< 100/> 100) | 24/27 | 48.3/6.00 | 0.008 | CA19-9 (< 100/> 100) | 1.485 | 0.591–3.793 | 0.400 |
CEA|| (< 5/> 5) | 37/15 | 27.4/26.6 | 0.810 | Â | Â | Â | Â |
Surgical procedure (Partial resection/segmentectomy / lobectomy) | 5/8/39 | 30.0/38.1/25.5 | 0.627 | Â | Â | Â | Â |
Lymphadenectomy (+/−) | 29/23 | 17.1/40.4 | 0.1027 |  |  |  |  |