Table 5 Univariate analysis of LR, RR, and DM of young breast cancer patients

Tumor size

< 0.01

< 0.01

< 0.01

T1

1.0

1.0

1.0

T2

0.8 (0.5–1.3)

0.40

0.9 (0.5–1.7)

0.85

1.9 (1.3–2.7)

< 0.01

T3

2.2 (1.1–4.5)

0.02

3.4 (1.6–7.0)

< 0.01

5.7 (3.7–8.7)

< 0.01

T4

8.5 (3.3–22.0)

< 0.01

9.2 (3.1–27.0)

< 0.01

13.7 (7.1–26.5)

< 0.01

Stage

< 0.01

< 0.01

< 0.01

I

1.0

1.0

1.0

II a

1.5 (0.8–2.9)

0.22

0.4 (0.2–1.1)

0.09

2.1 (1.2–3.5)

< 0.01

II b

2.0 (1.0–4.3)

0.06

2.0 (0.9–4.5)

0.08

3.4 (1.9–6.0)

< 0.01

III a

1.0 (0.4–2.7)

0.92

3.6 (1.7–7.5)

< 0.01

6.2 (3.6–10.6)

< 0.01

III b

7.8 (1.8–34.3)

< 0.01

4.3 (0.6–33.1)

0.16

14.8 (5.5–39.6)

< 0.01

III c

3.8 (1.5–9.5)

< 0.01

4.1 (1.8–9.1)

< 0.01

12.9 (7.6–21.8)

< 0.01

LN metastasis

< 0.01

<0.01

< 0.01

N0

1.0

1.0

1.0

N1

2.3 (1.4–3.7)

< 0.01

2.3 (1.1–4.6)

0.02

2.1 (1.5–3.0)

< 0.01

N2

1.0 (0.4–2.3)

0.95

5.9 (3.0–11.5)

< 0.01

3.8 (2.6–5.6)

< 0.01

N3

3.9 (2.1–7.3)

< 0.01

6.9 (3.3–14.5)

< 0.01

8.1 (5.6–11.8)

< 0.01

HG

0.09

0.81

0.21

I

1.0

1.0

1.0

II

0.6 (0.2–1.6)

0.26

0.7 (0.2–2.4)

0.60

1.9 (0.7–5.3)

0.19

III

1.1 (0.4–3.3)

0.86

1.0 (0.3–3.5)

0.97

2.5 (0.9–7.0)

0.08

Final surgery

0.13

0.30

< 0.01

Mastectomy

1.0

1.0

1.0

BCS

1.4 (0.9–2.3)

0.13

0.7 (0.4–1.3)

0.30

0.4 (0.3–0.7)

< 0.01

ER status

< 0.01

0.16

0.35

Positive

1.0

1.0

1.0

Negative

2.0 (1.3–3.1)

< 0.01

1.6 (1.0–2.7)

0.06

1.2 (0.9–1.6)

0.25

PR status

< 0.01

0.94

0.93

Positive

1.0

1.0

1.0

Negative

1.9 (1.2–2.9)

< 0.01

1.1 (0.7–1.9)

0.72

1.1 (0.8–1.4)

0.71

HER2 status

< 0.01

0.59

< 0.01

Positive

1.0

1.0

1.0

Negative

0.5 (0.3–0.8)

< 0.01

0.8 (0.4–1.4)

0.38

0.6 (0.4–0.8)

< 0.01

MS

< 0.01

0.66

< 0.01

HR+/HER2−

1.0

1.0

1.0

HR+/HER2+

1.7 (0.8–3.4)

0.15

1.0 (0.4–2.3)

0.94

1.5 (1.0–2.2)

0.06

HR−/HER2+

3.5 (1.8–6.7)

< 0.01

1.7 (0.8–3.9)

0.18

1.9 (1.2–2.9)

< 0.01

HR−/HER2−

1.5 (0.8–2.7)

0.20

0.9 (0.4–1.8)

0.73

0.7 (0.5–1.1)

0.15

NACT

0.04

< 0.01

< 0.01

No

1.0

1.0

1.0

Yes

1.8 (1.0–3.0)

0.04

2.5 (1.4–4.3)

< 0.01

2.9 (2.1–3.8)

< 0.01

ACT

0.18

0.70

0.29

A- and T-based

1.0

1.0

1.0

A-based

1.2 (0.7–2.2)

0.47

1.3 (0.7–2.5)

0.48

1.2 (0.8–1.7)

0.42

Radiotherapy

0.20

0.03

< 0.01

No

1.0

1.0

1.0

Yes

1.1 (0.7–1.8)

0.56

1.9 (1.1–3.3)

0.03

2.5 (1.8–3.5)

< 0.01

ET

< 0.01

0.09

0.22

No

1.0

1.0

1.0

Yes

0.5 (0.3–0.7)

< 0.01

0.7 (0.4–1.3)

0.30

1.1 (0.8–1.5)

0.71

OFS

0.52

< 0.01

< 0.01

No

1.0

1.0

1.0

Yes

1.2 (0.6–2.1)

0.64

3.4 (1.8–6.2)

< 0.01

3.7 (2.6–5.3)

< 0.01

TT

0.30

0.94

0.14

No

1.0

1.0

1.0

Yes

1.5 (0.7–3.4)

0.30

0.9 (0.3–2.6)

0.94

1.4 (0.9–2.3)

0.14