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Table 1 Demographic characteristics of young patients surgically treated between January 1, 2006, and December 31, 2014 (n = 1099)

From: Loco-regional recurrence trend and prognosis in young women with breast cancer according to molecular subtypes: analysis of 1099 cases

Characteristics

No. of patients (%)

BC family history

 Yes

113 (10.3)

 No

969 (88.2)

 Unknown

17 (1.5)

Reproductive history*

 Yes

827 (75.3)

 No

257 (23.4)

 Unknown

15 (1.4)

Breastfeeding history

 Yes

745 (67.8)

 No

337 (30.7)

 Unknown

17 (1.5)

Tumor size

 T1

420 (38.2)

 T2

508 (46.2)

 T3

88 (8.0)

 T4

16 (1.5)

 Tx

67 (6.1)

Stage

 I

282(25.7)

 II a

383 (34.8)

 II b

159 (14.5)

 III a

126 (11.5)

 III b

8 (0.7)

 III c

97 (8.8)

 Unknown

44 (4.0)

Lymph node metastasis

 N0

585 (53.2)

 N1

276(25.1)

 N2

124 (11.3)

 N3

94 (8.6)

 Unknown

20 (1.8)

Histological grade

Well differentiated

35 (3.2)

 Moderately differentiated

594 (54.0)

 Poorly differentiated

163 (14.8)

 Unknown

307 (27.9)

Pathological type

 Invasive ductal carcinoma

999 (90.9)

 Invasive lobular carcinoma

10 (0.9)

 Others

90 (8.2)

Final surgery

 Breast-conserving surgery

257 (23.4)

 Mastectomy

842 (76.6)

Biomarker subtype

 HR+/HER2−

594 (54.0)

 HR+/HER2+

120 (10.9)

 HR−/HER2+

75 (6.8)

 HR−/HER2−

201 (18.3)

 Unknown

109 (9.9)

Neoadjuvant chemotherapy

 Yes

176 (16.0)

 No

923 (84.0)

Adjuvant chemotherapy regimens

 Anthracycline-based

140 (12.7)

 Anthracycline- and taxane-based

884 (80.4)

 Unknown

67 (6.1)

 None

8 (0.7)

Radiotherapy

 Yes

557 (50.7)

 No

453 (41.2)

 Unknown

89 (8.1)

Endocrine therapy

 Yes

589 (53.6)

 No

316 (28.8)

 Unknown

194 (17.7)

Ovarian function suppression

 Yes

187 (17.0)

 No

545 (49.6)

 Unknown

367 (33.4)

Trastuzumab treatment

 Yes

85 (7.7)

 No

836 (76.1)

 Unknown

178 (16.2)

  1. BC, breast cancer; HR+, hormone receptor positive, HR− hormone receptor negative, HER2+ human epidermal growth factor 2 positive, HER2− human epidermal growth factor 2 negative
  2. *Reproductive history: Yes means they had children