Table 3 Subgroup analyses
From: Left-side vs. right-side hepatectomy for hilar cholangiocarcinoma: a meta-analysis
Variable | Subgroup | OS | 1-year survival | 3-year survival | 5-year survival | Overall morbidity | Major morbidity | PHLF | Mortality | R0 resection |
|---|---|---|---|---|---|---|---|---|---|---|
Region | Western | HR = 1.34; 95% CI, 0.95–1.89; P = 0.097; n = 4 | RR = 0.90; 95% CI, 0.72–1.13; P = 0.354 n = 2 | RR = 0.93; 95% CI, 0.73–1.19; P = 0.552 n = 3 | RR = 0.70; 95% CI, 0.52–0.94; P = 0.018 n = 4 | RR = 0.70; 95% CI, 0.57–0.87; P = 0.001 n = 2 | RR = 0.62; 95% CI, 0.42–0.91; P = 0.015 n = 2 | RR = 0.40; 95% CI, 0.09–1.82; P = 0.233 n = 1 | RR = 0.39; 95% CI, 0.17–0.88; P = 0.024 n = 3 | RR = 0.87; 95% CI, 0.76–0.99; P = 0.038 n = 3 |
|  | Eastern | HR = 1.19; 95% CI, 0.82–1.73; P = 0.362; n = 6 | RR = 1.08; 95% CI, 0.93–1.24; P = 0.315 n = 3 | RR = 0.96; 95% CI, 0.77–1.19; P = 0.681 n = 4 | RR = 0.97; 95% CI, 0.72–1.30; P = 0.836 n = 4 | RR = 0.92; 95% CI, 0.74–1.14; P = 0.434 n = 2 | RR = 0.88; 95% CI, 0.61–1.26; P = 0.477 n = 3 | RR = 0.16; 95% CI, 0.05–0.55; P = 0.003 n = 3 | RR = 0.42; 95% CI, 0.20–0.88; P = 0.021 n = 6 | RR = 1.00; 95% CI, 0.90–1.10; P = 0.958 n = 4 |
Year of publication | ≤2014 | HR = 1.39; 95% CI, 0.92–2.10; P = 0.113; n = 3 | RR = 0.90; 95% CI, 0.72–1.13; P = 0.354 n = 2 | RR = 0.53; 95% CI, 0.29–0.96; P = 0.037 n = 1 | RR = 0.63; 95% CI, 0.39–1.00; P = 0.051 n = 2 | RR = 0.86; 95% CI, 0.61–1.20; P = 0.377 n = 1 | n = 0 | n = 0 | RR = 0.32; 95% CI, 0.13–0.77; P = 0.011 n = 3 | RR = 0.90; 95% CI, 0.78–1.04; P = 0.141 n = 2 |
|  | >2014 | HR = 1.20; 95% CI, 0.87–1.65; P = 0.276; n = 7 | RR = 1.08; 95% CI, 0.93–1.24; P = 0.315 n = 3 | RR = 0.99; 95% CI, 0.84–1.18; P = 0.917 n = 6 | RR = 0.89; 95% CI, 0.70–1.12; P = 0.307 n = 6 | RR = 0.81; 95% CI, 0.68–0.97; P = 0.018 n = 3 | n = 5 | n = 4 | RR = 0.47; 95% CI, 0.23–0.96; P = 0.038 n = 6 | RR = 0.97; 95% CI, 0.88–1.07; P = 0.582 n = 5 |
Cases | > 41cases | HR = 1.24; 95% CI, 0.92–1.66; P = 0.154; n = 3 | RR = 1.08; 95% CI, 0.93–1.25; P = 0.303 n = 2 | RR = 0.93; 95% CI, 0.72–1.21; P = 0.594 n = 2 | RR = 0.84; 95% CI, 0.62–1.13; P = 0.248 n = 3 | RR = 0.85; 95% CI, 0.70–1.03; P = 0.102 n = 3 | RR = 0.76; 95% CI, 0.46–1.27; P = 0.295 n = 2 | RR = 0.38; 95% CI, 0.11–1.32; P = 0.127 n = 2 | RR = 0.32; 95% CI, 0.14–0.72; P = 0.006 n = 4 | RR = 0.95; 95% CI, 0.85–1.06; P = 0.369 n = 4 |
≤ 41cases | HR = 1.35; 95% CI, 0.82–2.23; P = 0.231; n = 7 | RR = 0.96; 95% CI, 0.77–1.19; P = 0.688 n = 3 | RR = 0.95; 95% CI, 0.77–1.18; P = 0.656 n = 5 | RR = 0.81; 95% CI, 0.61–1.08; P = 0.148 n = 5 | RR = 0.74; 95% CI, 0.60–0.91; P = 0.004 n = 1 | RR = 0.71; 95% CI, 0.52–0.97; P = 0.029 n = 3 | RR = 0.12; 95% CI, 0.03–0.55; P = 0.006 n = 2 | RR = 0.52; 95% CI, 0.24–1.10; P = 0.086 n = 5 | RR = 0.94; 95% CI, 0.84–1.05; P = 0.289 n = 3 |