Overexpression of DSCR1 prevents proliferation and predicts favorable prognosis in colorectal cancer patients

Table 1 Relationship between DSCR1 expression and clinicopathologic features of CRC patients

Characteristics	Case number	Test cohort			Case number	Validation cohort
Characteristics	Case number	DSCR1 negative	DSCR1 positive	p value	Case number	DSCR1 negative	DSCR1 positive	p value
Age				0.141				0.271
≤ 60	28	19	9		20	10	10
>60	42	20	22		38	25	13
Sex				0.808				0.417
male	41	22	19		33	18	15
female	29	17	12		25	17	8
Location				1.000				0.592
colon	38	21	17		32	18	14
rectum	32	18	14		26	17	9
Tumor side				0.9003				0.524
Left	32	13	19		25	12	13
Right	38	16	22		33	19	14
Tumor size				*0.018*				*0.046*
≤ 6 cm	36	15	21		31	15	16
>6 cm	34	24	10		27	20	7
Tumor differentiation				0.091				0.059
well/moderate	32	14	18		28	13	15
poor/undifferentiated	38	25	13		30	22	8
Lymph node metastasis				*0.013*				*0.016*
no	53	25	28		34	16	18
yes	17	14	3		24	19	5
Histological grade				*0.008*				0.593
I/II	20	6	14		27	15	12
III	50	33	17		31	20	11
Node stage				*0.016*				0.111
N0	41	17	24		27	13	14
N1	23	17	6		19	12	7
N2	6	5	1		12	10	2
TNM stage				*0.037*				*0.001*
I	5	2	3		15	1	14
II	35	15	20		18	11	7
III	30	22	8		19	17	2

ISSN: 1477-7819