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Table 3 Univariate and multivariate analyses of survival (Cox’s proportional hazards regression models)

From: SUVmax reduction predicts long-term survival in patients of non-pCR both in the tumor and lymph nodes after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma

Factor

Univariate

Multivariate

P-value

HR (95% CI)

P-value

OS

Age ( ≥65/<65)

0.0242a

4.1216 (1.1369-14.9423)

0.0311a

Gender (male/female)

0.9989

  

Location (middle, lower/upper)

0.1605

  

Differentiation (not poorly/poorly)

0.6711

  

cT (T3-4/T1-2)

0.9991

  

cN (N2-3/N1)

0.7055

  

cM (M1 (lymph node)/M0)

0.4804

  

pT (T3-4/T1-2)

0.2130

  

pN (N2-3/N1)

0.0965

  

SUVmax reduction rate in the primary lesion (<60%/≥60%)

0.0007a

8.3800 (2.3893–29.3915)

0.0009a

DSS

Age ( ≥65/<65)

0.0246a

5.2678 (1.2729–21.8008)

0.0219a

Gender (male/female)

0.9990

  

Location (middle, lower/upper)

0.2356

  

Differentiation (not poorly/poorly)

0.9992

  

cT (T3-4/T1-2)

0.9992

  

cN (N2-3/N1)

0.3436

  

cM (M1 (lymph node)/M0)

0.3277

  

pT (T3-4/T1-2)

0.4104

  

pN (N2-3/N1)

0.0969

  

SUVmax reduction rate in the primary lesion (<60%/≥60%)

0.0034a

7.6048 (1.9819–29.1798)

0.0031a

RFS

Age (≥65/<65)

0.1947

  

Gender (male/female)

0.2876

  

Location (middle, lower/upper)

0.0759

  

Differentiation (not poorly/poorly)

0.2910

  

cT (T3-4/T1-2)

0.9203

  

cN (N2-3/N1)

0.4032

  

cM (M1 (lymph node)/M0)

0.7506

  

pT (T3-4/T1-2)

0.0312a

2.5857 (0.8313–8.0423)

0.1008

pN (N2-3/N1)

0.0330a

0.6968 (0.1794–2.7072)

0.6019

SUVmax reduction rate in the primary lesion (<60%/≥60%)

0.0006a

6.2962 (1.4981–26.4625)

0.0120a

  1. OS overall survival, DSS disease-specific survival, RFS relapse-free survival, HR hazard ratio, CI confidence interval
  2. *Statistically significant