Actual survival after resection of primary colorectal cancer: results from a prospective multicenter study

Table 2 Characteristics of patients with potential cure and probability of cure estimated from the semiparametric mixture cure model

	Total NED, DOD, AWD (N = 621)	Observed 5-year survivors	% observed	Predicted cure
Gender
Male	335	256	76.4	82
Female	286	234	81.8	83.7
Age
< 70	340	280	82.4	88.5
≥ 70	281	210	74.7	80.1
BMI
1 (< 18.5)	17	15	88.2	75.6
2 (18.5–24.9)	228	181	79.4	85.5
3 (≥ 25.0)	368	289	87.5	84
Sarcopenia
No	254	211	83.1	86
Yes	246	196	79.7	82.8
Low muscle density
No	190	159	83.7	86.7
Yes	305	245	80.3	83
Sarcopenia + obesity
No	590	465	85	75.4
Yes	31	25	75.4	85.7
Diabetes mellitus
No	508	402	79.5	86.6
Yes	114	88	77.2	75.8
Decompensatio cordis
No	591	466	78.9	84.8
Yes	30	24	80	78.7
COPD
No	591	454	78.41	84.9
Yes	42	36	80	78.2
Charlson comorbidity index
0	336	266	79.2	88.8
1+	283	223	78.9	78.8
ASA score
I + II	526	409	78.1	83.7
III + IV	92	77	83.7	87.5
CEA
< 7ug/L	430	360	83.7	87.8
≥ 7ug/L	146	93	63.7	73.1
Tumor location
Colon	444	371	83.6	85.8
Rectum	177	119	67.2	80
T-stage
1	36	34	94.4	92.2
2	193	171	88.6	92.1
3	362	270	74.6	81.2
4	30	15	50	62.3
N-stage
0	336	303	90.2	92.7
1	134	103	76.9	82.9
2	80	33	41.3	50.1
X	71	51	71.8	83.4
Tumor stage
I	180	164	91.1	94.6
II	227	190	83.7	88.4
III	214	136	63.6	71
Tumor grade
Good	79	66	83.5	86.5
Moderate	470	377	80.2	85.7
Poor	53	33	62.3	73.1
Unknown/other	10	7	70	79.7
Radicality
R0	605	477	80	84.5
R1	15	12	78.8	77.5
Postoperative complications
No	266	298	83.9	90.4
Yes	355	192	72.2	76.8
Readmission < 30 days
No	552	438	79.5	94.1
Yes	68	52	76.5	87.1
Neoadjuvant therapy
No	462	383	82.9	85.7
Yes	158	106	67.1	79.9
Adjuvant chemotherapy
No	127	382	78.1	84
Yes	489	104	81.9	86.1

ISSN: 1477-7819