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Fig. 1 | World Journal of Surgical Oncology

Fig. 1

From: A 4-gene-based hypoxia signature is associated with tumor immune microenvironment and predicts the prognosis of pancreatic cancer patients

Fig. 1

Characterization of hypoxia risk score to predict prognosis of PAC. a Protein–protein interactions among 200 hypoxia-associated genes. b The 50 genes with the highest interaction degrees were extracted. c Sixteen hypoxia genes associated with patient’ OS were confirmed by univariate Cox regression. d Four hypoxia-related genes were chosen to establish a hypoxia risk model by multivariate Cox regression. e, f Spearman correlation analysis of four hypoxia genes in the TCGA and GEO databases

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