Table 4 Univariate and multivariate associations between covariates and the composite primary endpoint of recurrence or dead in CRC patients with stage II/III

 Did not receive

1.0 (reference)

1.0(reference)

 Received

0.53(0.32–0.86)

.01

0.50(0.30–0.82)

.006

 Female

1.0(reference)

1.0(reference)

 Male

1.31(0.80–2.13)

.29

1.37(0.83–2.27)

.22

 <50

1.0(reference)

1.0(reference)

 ≥50

1.54(0.71–3.34)

.28

1.50(0.67–3.32)

.33

 Right colon

1.0(reference)

1.0(reference)

 Left colon

1.42(0.75–2.69)

.28

1.33(0.68–2.59)

.40

 Rectal

1.11(0.63–1.95)

.71

0.92(0.51–1.66)

.78

 <5 cm

1.0(reference)

1.0(reference)

 ≥5cm

1.01(0.64–1.58)

.97

1.13(0.70–1.81)

.62

 N0

1.0(reference)

1.0(reference)

 N1

2.12(1.24–3.61)

.006

2.23(1.23–4.05)

.008

 N2

2.64(1.39–5.00)

.003

2.84(1.37–5.88)

.005

 II

1.0(reference)

1.0(reference)

 III

2.26(1.37–3.73)

.002

2.37(1.33–4.20)

.003

 Well

1.0(reference)

1.0(reference)

 Moderate

0.88(0.22–3.59)

.86

0.44(0.10–1.94)

.28

 Poor

0.80(0.15–4.38)

.80

0.33(0.05–2.05)

.24

 No

1.0(reference)

1.0(reference)

 Yes

1.55(0.99–2.43)

.06

1.34(0.81–2.22)

.26

 II

1.0(reference)

1.0(reference)

 III/IV

1.29(0.83–2.03)

.26

1.54(0.96–2.49)

.07

 Did not receive

1.0(reference)

1.0(reference)

 Received

0.66(0.42–1.04)

.07

0.53(0.33–0.85)

.009