Table 1 Baseline characteristics of patients
Characteristic | Patients, no. Surgery without IOC (N=220) | Surgery plus IOC (N= 171) | P value |
|---|---|---|---|
Age, mean (SD), y | 60.4(9.7) | 60.6(8.7) | .85 |
Sex | |||
 Male | 137 | 114 | .37 |
 Female | 83 | 57 |  |
Hypertension | |||
 Yes | 57 | 49 | .55 |
 No | 163 | 122 |  |
Diabetic mellitus | |||
 Yes | 38 | 30 | .94 |
 No | 182 | 141 |  |
 CEA, mean (SD), ng/mL | 8.41(14.90) | 9.07(15.41) | .67 |
Tumor location | |||
 Right colon | 64 | 39 | .37 |
 Left colon | 48 | 40 |  |
 Rectal | 108 | 92 |  |
 Tumor size, mean (SD), cm | 4.8(1.6) | 4.6(1.7) | .42 |
Pathologic T category | |||
 T1 | 4 | 3 | .84 |
 T2 | 8 | 9 |  |
 T3 | 195 | 147 |  |
 T4 | 13 | 12 |  |
Pathologic N category | |||
 N0 | 96 | 80 | .76 |
 N1 | 93 | 66 |  |
 N2 | 31 | 25 |  |
TNM stage | |||
 II | 96 | 80 | .54 |
 III | 124 | 91 |  |
Differentiation | |||
 Well | 6 | 4 | .44 |
 Moderate | 204 | 154 |  |
 Poor | 10 | 13 |  |
Pathological type | |||
 Tubular adenocarcinoma | 209 | 159 | .12 |
 Mucinous adenocarcinoma | 7 | 3 |  |
 Mixed adenocarcinoma | 4 | 9 |  |
Vascular invasion | |||
 Yes | 86 | 65 | .83 |
 No | 134 | 106 |  |
Postoperative chemotherapy | |||
 Yes | 122 | 92 | .75 |
 No | 98 | 79 |  |