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Table 4 Univariate and multivariate Cox analysis of clinical characteristics on three sets

From: Comprehensive analyses of correlation and survival reveal informative lncRNA prognostic signatures in colon cancer

Variables

Univariate

Multivariate

 

HR (95% CI for HR)

p value

Coef

z

p

Training set

Age

1 (1–1.1)

0.016

0.0442637

3.290

0.0010

Gender

0.92 (0.54–1.6)

0.75

0.0004572

0.002

0.9987

Tumor stage

2.2 (1.6–3)

3.3e −07

0.4570372

1.739

0.0820

Tumor invasion (T)

2.9 (1.8–4.8)

1.8e-05

0.6198692

1.871

0.0614

Lymph node (N)

2.2 (1.6–2.9)

9.5e −07

0.2121219

0.860

0.3895

Metastasis (M)

1.7 (1.2–2.3)

0.001

0.2204375

1.065

0.2869

Risk score

2 (1.6–2.6)

6.4e −08

0.6528934

4.518

6.24e −06

Testing set

Age

1 (0.98–1)

0.82

0.02209

1.359

0.17421

Gender

0.76 (0.36–1.6)

0.49

−0.19816

−0.454

0.65005

Tumor stage

2.8 (1.7–4.7)

6.2e −05

0.94479

2.720

0.00653

Tumor invasion (T)

1.8 (0.86–3.8)

0.12

−0.10185

−0.203

0.83914

Lymph node (N)

2.1 (1.3–3.4)

0.0034

−0.10574

−0.287

0.77424

Metastasis (M)

1.6 (1–2.5)

0.031

0.51952

1.630

0.10307

Risk score

1.4 (1–1.8)

0.027

0.34615

2.071

0.03837

Total set

Age

1 (1–1)

0.041

0.03938

3.833

0.000127

Gender

0.89 (0.58–1.4)

0.6

−0.02656

−0.115

0.908684

Tumor stage

2.3 (1.8–2.9)

1.5e −10

0.59692

2.802

0.005076

Tumor invasion (T)

2.6 (1.7–4)

5e −06

0.45556

1.691

0.090824

Lymph node (N)

2.1 (1.6–2.7)

2.1e −08

0.08203

0.394

0.693225

Metastasis (M)

1.6 (1.3–2.1)

0.00012

0.31324

1.870

0.061471

Risk score

1.6 (1.4–2)

2.8e −08

0.49875

4.845

1.27e −06