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Table 2 Comparison of postoperative chemotherapy between the UFS and NAC groups

From: Effect and limitation of neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma: consideration from a new perspective

Postoperative chemotherapy

Total (n = 131)

UFS (n = 64)

NAC (n = 67)

NAC (GS) (n = 62)

P value* (UFS v.s. NAC)

P value* (UFS v.s. NAC (GS))

Gemcitabine (monotherapy or combination therapy)

80

39

41

36

0.855

1.000

S-1 (monotherapy or combination therapy)

93

45

48

45

0.692

0.681

CDDP plus gemcitabine or S-1

6

6

0

0

0.013

0.028

Erlotinib plus gemcitabine

2

2

0

0

0.244

0.496

Paclitaxel (monotherapy)

1

1

0

0

1.000

0.496

GS

7

4

3

3

0.718

1.000

GnP

40

14

26

23

0.035

0.051

FOLFIRINOX

12

2

10

10

0.030

0.014

  1. UFS upfront surgery, NAC neoadjuvant chemotherapy, S-1 tegafur/gimeracil/oteracil, GS gemcitabine plus S-1, CDDP cisplatin, GnP gemcitabine plus nab-paclitaxel, FOLFIRINOX 5-fluorouracil, leucovorin, irinotecan, oxaliplatin
  2. *Cases without information are excluded from calculation of P values