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Table 2 Comparison of postoperative chemotherapy between the UFS and NAC groups

From: Effect and limitation of neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma: consideration from a new perspective

Postoperative chemotherapy Total (n = 131) UFS (n = 64) NAC (n = 67) NAC (GS) (n = 62) P value* (UFS v.s. NAC) P value* (UFS v.s. NAC (GS))
Gemcitabine (monotherapy or combination therapy) 80 39 41 36 0.855 1.000
S-1 (monotherapy or combination therapy) 93 45 48 45 0.692 0.681
CDDP plus gemcitabine or S-1 6 6 0 0 0.013 0.028
Erlotinib plus gemcitabine 2 2 0 0 0.244 0.496
Paclitaxel (monotherapy) 1 1 0 0 1.000 0.496
GS 7 4 3 3 0.718 1.000
GnP 40 14 26 23 0.035 0.051
FOLFIRINOX 12 2 10 10 0.030 0.014
  1. UFS upfront surgery, NAC neoadjuvant chemotherapy, S-1 tegafur/gimeracil/oteracil, GS gemcitabine plus S-1, CDDP cisplatin, GnP gemcitabine plus nab-paclitaxel, FOLFIRINOX 5-fluorouracil, leucovorin, irinotecan, oxaliplatin
  2. *Cases without information are excluded from calculation of P values