Fig. 3

Circ-KIAA0907 sponged miR-96-5p. a The sequences of circ-KIAA0907 containing the miR-96-5p binding sites or mutant binding sites were shown. Dual-luciferase reporter assay b, c and RIP assay d, e were used to assess the interaction between circ-KIAA0907 and miR-96-5p. f The expression of miR-96-5p in 59 paired OSCC cancer tissues and adjacent normal tissues was examined by qRT-PCR. g Pearson correlation analysis was employed to analyze the correlation between circ-KIAA0907 and miR-96-5p expression in OSCC cancer tissues. h MiR-96-5p expression in OSCC cells (HSC6 and OECM1) and HOK cells was measured by qRT-PCR. i The transfection efficiency of si-circ-KIAA0907 was evaluated by detecting circ-KIAA0907 expression using qRT-PCR. j, k HSC6 and OECM1 cells were transfected with pCD5-ciR, circ-KIAA0907, si-con, or si-circ-KIAA0907. The expression of miR-96-5p was tested by qRT-PCR. *P < 0.05, **P < 0.01, ***P < 0.001