Table 2 Frequency of histological upgrade and related variables among 99 patients who underwent excision
From: The lobular neoplasia enigma: management and prognosis in a long follow-up case series
Total (99) | Upgrade | p value | |||
|---|---|---|---|---|---|
No (71) | Yes (28) | ||||
Median age at diagnosis (interval) | 55 (36–74) | 52 (36–74) | 59 (39–76) | 0.003 | |
Age cutoff | < 54 years | 46 (46.5%) | 39 (54.9%) | 7 (25%) | 0.006 |
≥ 54 years | 53 (53.5%) | 32 (45.1%) | 21 (75%) | ||
Family history for BC missing 7 | No | 63 (63.6%) | 46 (70.8%) | 17 (63%) | 0.528 |
Yes | 29 (36.4%) | 19 (29.2%) | 10 (27%) | ||
Previous breast surgery missing 7 | No | 72 (78.3%) | 54 (83%) | 18 (66.7%) | 0.149 |
Yes | 20 (21.7%) | 11 (17%) | 9 (33.3%) | ||
Diagnostic procedure | Core needle biopsy | 52 (52.5%) | 36 (50.7%) | 16 (57.1%) | 0.563 |
Vacuum-assisted biopsy | 47 (47.5%) | 35 (49.3%) | 12 (42.9%) | ||
Radiological features | Microcalcifications | 70 (70.7%) | 51 (71.8%) | 19 (67.9%) | 0.722 |
Mass | 20 (20.2%) | 13 (18.3%) | 7 (25%) | ||
Architectural distortion | 9 (9.1%) | 7 (9.8%) | 2 (7.1%) | ||
Radiological diameter (mm) missing 16 | < 10 | 47 (56.7%) | 36 (60%) | 11 (47.9%) | 0.61 |
10-20 | 29 (34.9%) | 20 (33.3%) | 9 (39.1%) | ||
> 20 | 7 (8.4%) | 4 (6.7%) | 3 (13%) | ||
BI-RADS category missing 7 | BI-RADS 3 | 65 (70.7%) | 51 (78.5%) | 14 (51.9%) | 0.03 |
BI-RADS 4 | 23 (25%) | 12 (18.5%) | 11 (40.7%) | ||
BI-RADS 5 | 4 (4.3%) | 2 (3%) | 2 (7.4%) | ||
Biopsy histology | ALH | 27 (27.2%) | 24 (33.9%) | 3 (10.7%) | 0.013 |
LCIS | 57 (57.6%) | 40 (56.3%) | 17 (60.7%) | ||
HG-LN | 15 (15.2%) | 7 (9.8%) | 8 (28.6%) | ||
Associated lesions | No | 66 (66.6%) | 45 (63.4%) | 21 (75%) | 0.296 |
Yes | 33 (33.3%) | 26 (36.6%) | 7 (25%) | ||