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Table 1 Clinico-pathological features of the study population according to histological diagnosis (ALH, LCIS, HG-LN)

From: The lobular neoplasia enigma: management and prognosis in a long follow-up case series

Clinico-pathological features

ALH (44)

LCIS (63)

HG-LN (15)

Total (122)

p value

Median age at diagnosis (interval)

 

54 (39–77)

52 (36–74)

56 (39–76)

54 (36–77)

0.714

Family history for BC

No

25 (56.9%)

41 (65%)

10 (66.7%)

76 (62.3%)

0.922

Yes

15 (34.2%)

17 (27%)

4 (26.6%)

36 (29.5%)

Missing

4 (9%)

5 (8%)

1 (6.7%)

10 (8.2%)

Previous breast surgery

No

30 (68.1%)

46 (73%)

11 (73.3%)

87 (71.3%)

0.919

Yes

9 (20.5%)

13 (20.6%)

3 (20%)

25 (20.5%)

Missing

5 (11.4%)

4 (6.3%)

1 (6.7%)

8 (8.2%)

Diagnostic procedure

Core needle biopsy

25 (56.8%)

27 (42.9%)

9 (60%)

61 (50%)

0.252

Vacuum-assisted biopsy

19 (43.2%)

36 (57.1%)

6 (40%)

61 (50%)

Radiological features

Microcalcifications

35 (79.6%)

45 (71.5%)

10 (66.7%)

90 (73.8%)

0.456

Opacity

7 (15.9%)

12 (19%)

2 (13.3%)

21 (17.2%)

Architectural distortion

2 (4.5%)

6 (9.5%)

3 (20%)

11 (9%)

Radiological diameter (mm)

< 10

18 (41%)

33 (52.3%)

6 (40%)

57 (46.7%)

0.507

10–20

14 (31.8%)

17 (27%)

3 (20%)

34 (27.9%)

> 20

6 (13.6%)

3 (4.8%)

2 (13.4%)

11 (9%)

Missing

6 (13.6%)

10 (15.9%)

4 (26.6%)

20 (16.4%)

BI-RADS category

BI-RADS 3

32 (72.7%)

43 (68.3%)

6 (40%)

81 (66.4%)

0.001

BI-RADS 4

11 (25%)

13 (20.6%)

6 (40%)

30 (24.6%)

BI-RADS 5

0

1 (1.6%)

3 (20%)

4 (3.3%)

Missing

1 (2.3%)

6 (9.5%)

0

7 (5.7%)

Associated lesions

No

28 (63.6%)

43 (68.2%)

13 (86.7%)

84 (68.9%)

0.248

Yes

16 (36.4%)

20 (31.8%)

2 (13.3%)

38 (31.1%)