From: The lobular neoplasia enigma: management and prognosis in a long follow-up case series
Clinico-pathological features | ALH (44) | LCIS (63) | HG-LN (15) | Total (122) | p value | |
---|---|---|---|---|---|---|
Median age at diagnosis (interval) | 54 (39–77) | 52 (36–74) | 56 (39–76) | 54 (36–77) | 0.714 | |
Family history for BC | No | 25 (56.9%) | 41 (65%) | 10 (66.7%) | 76 (62.3%) | 0.922 |
Yes | 15 (34.2%) | 17 (27%) | 4 (26.6%) | 36 (29.5%) | ||
Missing | 4 (9%) | 5 (8%) | 1 (6.7%) | 10 (8.2%) | ||
Previous breast surgery | No | 30 (68.1%) | 46 (73%) | 11 (73.3%) | 87 (71.3%) | 0.919 |
Yes | 9 (20.5%) | 13 (20.6%) | 3 (20%) | 25 (20.5%) | ||
Missing | 5 (11.4%) | 4 (6.3%) | 1 (6.7%) | 8 (8.2%) | ||
Diagnostic procedure | Core needle biopsy | 25 (56.8%) | 27 (42.9%) | 9 (60%) | 61 (50%) | 0.252 |
Vacuum-assisted biopsy | 19 (43.2%) | 36 (57.1%) | 6 (40%) | 61 (50%) | ||
Radiological features | Microcalcifications | 35 (79.6%) | 45 (71.5%) | 10 (66.7%) | 90 (73.8%) | 0.456 |
Opacity | 7 (15.9%) | 12 (19%) | 2 (13.3%) | 21 (17.2%) | ||
Architectural distortion | 2 (4.5%) | 6 (9.5%) | 3 (20%) | 11 (9%) | ||
Radiological diameter (mm) | < 10 | 18 (41%) | 33 (52.3%) | 6 (40%) | 57 (46.7%) | 0.507 |
10–20 | 14 (31.8%) | 17 (27%) | 3 (20%) | 34 (27.9%) | ||
> 20 | 6 (13.6%) | 3 (4.8%) | 2 (13.4%) | 11 (9%) | ||
Missing | 6 (13.6%) | 10 (15.9%) | 4 (26.6%) | 20 (16.4%) | ||
BI-RADS category | BI-RADS 3 | 32 (72.7%) | 43 (68.3%) | 6 (40%) | 81 (66.4%) | 0.001 |
BI-RADS 4 | 11 (25%) | 13 (20.6%) | 6 (40%) | 30 (24.6%) | ||
BI-RADS 5 | 0 | 1 (1.6%) | 3 (20%) | 4 (3.3%) | ||
Missing | 1 (2.3%) | 6 (9.5%) | 0 | 7 (5.7%) | ||
Associated lesions | No | 28 (63.6%) | 43 (68.2%) | 13 (86.7%) | 84 (68.9%) | 0.248 |
Yes | 16 (36.4%) | 20 (31.8%) | 2 (13.3%) | 38 (31.1%) |