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Fig. 8 | World Journal of Surgical Oncology

Fig. 8

From: Circ_0082182 promotes oncogenesis and metastasis of colorectal cancer in vitro and in vivo by sponging miR-411 and miR-1205 to activate the Wnt/β-catenin pathway

Fig. 8

Circ_0082182 facilitated CRC tumorigenesis and EMT in vivo by activating the miR-411/miR-1205-mediated Wnt/β-catenin pathway. a Tumor volume was lower in sh-circ group than that in sh-NC group. b Tumors were excised and tumor weight was inhibited in sh-circ group by comparison with sh-NC group. c, d The circ_0082182 expression was downregulated (c) and miR-411/miR-1205 levels were increased (d) by sh-circ. e Silence of circ_0082182 inactivated the Wnt/β-catenin pathway and EMT process in tumor tissues. **P < 0.01

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