Fig. 6

Circ_0082182 acted as a carcinogene in CRC by sponging miR-411 and miR-1205. a The inhibitory efficiencies of anti-miR-411 and anti-miR-1205 were shown to be great via qRT-PCR detection. b–d Inhibitor of miR-411 or miR-1205 eliminated the sh-circ-induced proliferation inhibition (b, c) and cell cycle arrest (d). e, f The promoting effects of sh-circ on cell apoptotic rate (e) and caspase3/caspase9 activities (f) were relieved by anti-miR-411 or anti-miR-1205. g, h Sh-circ-mediated inhibition of cell migration (g) and invasion (h) was restored by miR-411 or miR-1205 inhibitor. *P < 0.05, **P < 0.01