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Fig. 4 | World Journal of Surgical Oncology

Fig. 4

From: Circ_0082182 promotes oncogenesis and metastasis of colorectal cancer in vitro and in vivo by sponging miR-411 and miR-1205 to activate the Wnt/β-catenin pathway

Fig. 4

Circ_0082182 targeted miR-411 and miR-1205 in CRC cells. a, b Circinteractome showed the binding sites between circ_0082182 and miR-411 (a) or miR-1205 (b). c, e The interaction between circ_0082182 and miR-411 or miR-1205 was validated using the dual-luciferase reporter assay (c, d) and Bio-coupled RNA pull-down assay (e). f, g The expression levels of miR-411 and miR-1205 were downregulated in CRC cells (f) and tissues (g). h Knockdown of circ_0082182 induced the upregulation of miR-411 and miR-1205 in HCT116 and CaCo-2 cells. **P < 0.01

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World Journal of Surgical Oncology

ISSN: 1477-7819

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