Fig. 2

Circ_0082182 contributed to cell proliferation and cell cycle progression while reduced apoptosis in CRC cells. a Circ_0082182 expression was knocked down by sh-circ in HCT116 and CaCo-2 cells. b–d Cell proliferation by CCK-8 assay (b, c) and colony formation (d) assay was inhibited after circ_0082182 was downregulated. e, f Cell cycle progression by flow cytometry was blocked by the knockdown of circ_0082182. g, i Cell apoptotic rate (g, h) and caspase3/caspase9 activities (i) were increased in sh-circ group relative to sh-NC group. *P < 0.05, **P < 0.01.