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Table 1 Univariable analysis for postoperative complications—OR (p value)

From: Preoperative C-reactive protein and other inflammatory markers as predictors of postoperative complications in patients with colorectal neoplasia

 

Ileus

Wound infection/dehiscence/hernia

Anastomotic leak

Sepsis

Embolism

Renal

Resp

Cardio

Neuro

Clavien Dindo > 0

Clavien-Dindo 345

Age ≥ 65

0.8 (0.640)

0.7 (0.608)

1.0 (0.968)

1.2 (0.819)

0.5 (0.284)

2.2 (0.220)

2.8 (0.060)

3.1 (0.060)

4.0 (0.161)

1.8 (0.048)

1.6 (0.215)

Male sex

1.0 (0.948)

1.4 (0.611)

1.7 (0.054)

3.7 (0.195)

0.6 (0.461)

1.4 (0.585)

1.6 (0.292)

1.2 (0.670)

2.2 (0.330)

1.3 (0.364)

1.8 (0.221)

BMI ≥ 30

0.9 (0.882)

1.2 (0.781)

0.7 (0.145)

5.2 (0.040)

1.9 (0.419)

1.2 (0.746)

0.7 (0.559)

0.5 (0.333)

2.5 (0.255)

1.0 (0.928)

1.6 (0.255)

Smoker

1.2 (0.862)

1.5 (0.622)

1.3 (0.821)

1.0 (0.981)

2.1 (0.370)

3.7 (0.25)

3.4 (0.010)

2.4 (0.125)

1.0 (0.981)

1.8 (0.164)

2.3 (0.060)

Cardiovascular

2.1 (0.184)

1.0 (0.990)

1.2 (0.849)

1.8 (0.443)

0.8 (0.762)

0.8 (0.662)

2.0 (0.099)

3.6 (0.004)

1.2 (0.814)

1.3 (0.359)

1.1 (0.769)

Respiratory

1.2 (0.789)

1.0 (0.988)

0.8 (0.828)

0.7 (0.693)

1.3 (0.729)

0.9 (0.882)

1.3 (0.613)

0.2 (0.064)

0.5 (0.489)

1.2 (0.636)

0.4 (0.065)

Renal

0.7 (0.685)

1.0 (0.982)

2.1 (0.396)

0.7 (0.713)

2.6 (0.198)

2.7 (0.063)

1.7 (0.269)

2.8 (0.026)

2.1 (0.295)

1.8 (0.096)

1.7 (0.205)

Diabetes

(0.368)

(0.999)

1.1 (0.942)

0.9 (0.923)

1.9 (0.455)

3.7 (0.012)

1.4 (0.519)

1.3 (0.647)

2.9 (0.134)

0.9 (0.797)

1.1 (0.772)

Autoimmune

1.1 (0.901)

0.7 (0.696)

3.2 (0.174)

2.5 (0.269)

2.1 (0.374)

1.4 (0.590)

2.7 (0.036)

1.5 (0.505)

0.7 (0.785)

2.5 (0.025)

2.9 (0.010)

Malignant tumors

1.2 (0.849)

0.9 (0.926)

0.5 (0.519)

(0.999)

(0.999)

1.6 (0.674)

0.5 (0.209)

1.0 (0.953)

0.9 (0.330)

1.2 (0.702)

2.2 (0.290)

Rectal tumous

0.6 (0.528)

0.4 (0.333)

0.8 (0.181)

(0.354)

1.2 (0.862)

1.1 (0.802)

0.8 (0.753)

2.3 (0.071)

(0.214)

0.6 (0.101)

0.4 (0.080)

Open approach*

2.8 (0.070)

1.0 (0.952)

2.1 (0.376)

3.3 (0.108)

0.6 (0.621)

3.7 (0.010)

2.7 (0.024)

1.8 (0.255)

3.6 (0.050)

3.2 (0.001)

2.0 (0.072)

Hemoglobin < 10 g/dl

2.8 (0.093)

0.6 (0.665)

1.2 (0.893)

4.7 (0.033)

3.7 (0.064)

0.9 (0.873)

0.8 (0.742)

0.6 (0.478)

3.1 (0.108)

2.3 (0.040)

1.6 (0.299)

WCC < 4× 109/L

1.0 (0.721)

1.0 (0.755)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.498)

(0.999)

WCC > 11× 109/L

1.3 (0.786)

(0.999)

(0.999)

2.8 (0.345)

(0.999)

4.4 (0.025)

3.9 (0.024)

3.1 (0.090)

(0.999)

6.2 (0.008)

8.3 (0.000)

Platelet < 150× 109/L

(0.999)

(0.999)

10.3 (0.018)

8.5 (0.032)

(0.999)

3.3 (0.277)

12.9 (0.001)

2.5 (0.402)

(0.999)

1.6 (0.621)

2.9 (0.225)

Platelet > 400× 109/L

1.2 (0.855)

(0.999)

(0.999)

2.5 (0.394)

5.4 (0.030)

4.0 (0.038)

1.3 (0.743)

3.0 (0.104)

15.8 (0.000)

6.9 (0.005)

6.8 (0.000)

Lymphocytes < 1× 109/L

3.1 (0.048)

2.0 (0.315)

2.3 (0.324)

1.9 (0.462)

0.6 (0.677)

0.6 (0.548)

1.5 (0.411)

1.5 (0.471)

1.3 (0.740)

1.4 (0.343)

1.9 (0.105)

Neutrophils < 2× 109/L

1.0 (0.719)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.493)

(0.999)

Neutrophils > 8× 109/L

1.1 (0.913)

(0.999)

(0.999)

2.3 (0.437)

2.0 (0.529)

5.7 (0.003)

4.5 (0.006)

1.5 (0.625)

1.7 (0.615)

7.4 (0.003)

5.8 (0.000)

PLR < 61

1.0 (0.799)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

PLR > 239

2.3 (0.146)

1.1 (0.915)

1.3 (0.790)

1.0 (0.997)

2.6 (0.170)

1.6 (0.800)

0.7 (0.595)

0.8 (0.715)

3.3 (0.066)

1.7 (0.080)

2.1 (0.041)

NLR < 0.83

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

(0.999)

NLR > 3.92

1.5 (0.523)

2.4 (0.172)

4.8 (0.051)

0.9 (0.908)

1.4 (0.664)

3.2 (0.020)

2.3 (0.044)

1.8 (0.198)

3.0 (0.096)

3.4 (0.000)

3.9 (0.000)

CRP ≥ 5 mg/L

2.2 (0.356)

1.6 (0.593)

5.7 (0.079)

(0.052)

(0.024)

15.4 (0.001)

4.5 (0.007)

7.6 (0.003)

(0.052)

16.9 (0.000)

20.5 (0.000)

CRP ≥ 10 mg/L

2.4 (0.281)

1.0 (0.008)

10.1 (0.014)

1.1 (0.002)

10.1 (0.014)

16.9 (0.001)

10.4 (0.000)

3.6 (0.021)

1.1 (0.002)

106.3(0.000)

63.3 (0.000)

CEA ≥ 3 ng/mL

1.1 (1.000)

0.2 (0.123)

0.3 (0.373)

1.1 (0.872)

1.5 (0.575)

1.6 (0.406)

1.0 (0.935)

1.5 (0.425)

3.0 (0.254)

1.9 (0.036)

1.3 (0.551)

T stage ≥ 4

2.3 (0.213)

(0.999)

4.7 (0.073)

1.1 (0.931)

(0.600)

1.0 (0.987)

1.1 (0.876)

2.7 (0.076)

2.0 (0.413)

2.6 (0.033)

1.6 (0.328)

Node positive

0.3 (0.123)

2.2 (0.254)

2.6 (0.294)

2.3 (0.276)

1.0 (0.997)

0.8 (0.725)

0.8 (0.672)

1.2 (0.667)

2.2 (0.254)

0.9 (0.594)

1.0 (0.897)

Moderate/poorly differentiated

3.4 (0.220)

0.6 (0.437)

0.4 (0.351)

1.8 (0.587)

0.9 (0.876)

0.8 (0.705)

1.3 (0.670)

0.4 (0.034)

0.6 (0.437)

1.0 (0.926)

0.8 (0.628)

  1. Results expressed as odds ratios (OR) with p values in brackets. Variables with p < 0.25 in this table are included for multivariable analysis. Where there were null values in contingency tables for univariate analysis, OR was not calculated and Fisher’s exact test used for p value and insertion to multivariate analysis where < 0.25. *versus laparoscopic