Geriatric nutritional risk index predicts cancer prognosis in patients with local advanced rectal cancer undergoing chemoradiotherapy followed by curative surgery

Table 2 Association between GNRI and clinicopathological factors in patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiotherapy

Category	GNRI high (> 104.25)	GNRI low (< 104.25)	P value
Age, years
≤63	36	12	0.0013
> 63	19	26
Sex
Male	40	28	0.92
Female	15	10
Pathological T
pT0-2	28	11	0.035
pT3-4	27	27
Pathological N
pN0	31	22	0.88
pN1-2	24	16
Histology
Well/moderate	49	32	0.49
Poorly/signet/mucinous	6	6
Lymphatic invasion
Absent	31	22	0.88
Present	24	16
Venous invasion
Absent	34	23	0.90
Present	21	15
Pathological response
Non-responder (grade0/1a/1b)	32	27	0.21
Responder (grade2/3)	23	11
Radiation
Short course	14	10	0.93
Long course	41	28
Adjuvant chemotherapy
Yes	42	23	0.10
No	13	15
CA19-9 (ng/ml)
≤ 37.0	47	28	0.16
> 37.0	8	10
CEA (ng/ml)
≤ 5	29	15	0.21
> 5	26	23
Recurrence
Absent	40	18	0.040
Local	4	7
Distant	11	13

Note: Data in the table are the number of patients in each category
GNRI geriatric nutritional risk index, CA19-9 carbohydrate antigen 19-9, CEA carcinoembryonic antigen

ISSN: 1477-7819