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Table 1 Baseline characteristics of patients in the total, training, and validation cohort

From: Identification and validation of a miRNA-related expression signature for tumor mutational burden in colorectal cancer

Characteristics Total cohort (N = 457) Training cohort, (N = 275) Validation cohort (N = 182) P value
Age
 ≤ 65 205 (44.86%) 128 (46.55%) 77 (42.31%) 0.4262
 > 65 252 (55.14%) 147 (53.45%) 105 (57.69%)
Gender
 Female 221 (48.36%) 138 (50.18%) 83 (45.6%) 0.3882
 Male 236 (51.64%) 137 (49.82%) 99 (54.4%)
Stage
 Stages I–II 246 (53.83%) 144 (52.36%) 102 (56.04%) 0.3331
 Stages III–IV 196 (42.89%) 124 (45.09%) 72 (39.56%)
 Not available 15 (3.28%) 7 (2.55%) 8 (4.4%)
T
 T1–2 89 (19.47%) 52 (18.91%) 37 (20.33%) 0.6735
 T3–4 367 (80.31%) 222 (80.73%) 145 (79.67%)
 Tis 1 (0.22%) 1 (0.36%) 0 (0%)
M
 M0 326 (71.33%) 194 (70.55%) 132 (72.53%) 0.8493
 M1 68 (14.88%) 43 (15.64%) 25 (13.74%)
 MX/not available 63 (13.79%) 38 (13.82%) 25 (13.74%)
N
 N0 261 (57.11%) 149 (54.18%) 112 (61.54%) 0.2282
 N1–2 195 (42.67%) 125 (45.45%) 70 (38.46%)
 NX 1 (0.22%) 1 (0.36%) 0 (0%)