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Table 1 Baseline characteristics of patients in the total, training, and validation cohort

From: Identification and validation of a miRNA-related expression signature for tumor mutational burden in colorectal cancer

Characteristics

Total cohort (N = 457)

Training cohort, (N = 275)

Validation cohort (N = 182)

P value

Age

 ≤ 65

205 (44.86%)

128 (46.55%)

77 (42.31%)

0.4262

 > 65

252 (55.14%)

147 (53.45%)

105 (57.69%)

Gender

 Female

221 (48.36%)

138 (50.18%)

83 (45.6%)

0.3882

 Male

236 (51.64%)

137 (49.82%)

99 (54.4%)

Stage

 Stages I–II

246 (53.83%)

144 (52.36%)

102 (56.04%)

0.3331

 Stages III–IV

196 (42.89%)

124 (45.09%)

72 (39.56%)

 Not available

15 (3.28%)

7 (2.55%)

8 (4.4%)

T

 T1–2

89 (19.47%)

52 (18.91%)

37 (20.33%)

0.6735

 T3–4

367 (80.31%)

222 (80.73%)

145 (79.67%)

 Tis

1 (0.22%)

1 (0.36%)

0 (0%)

M

 M0

326 (71.33%)

194 (70.55%)

132 (72.53%)

0.8493

 M1

68 (14.88%)

43 (15.64%)

25 (13.74%)

 MX/not available

63 (13.79%)

38 (13.82%)

25 (13.74%)

N

 N0

261 (57.11%)

149 (54.18%)

112 (61.54%)

0.2282

 N1–2

195 (42.67%)

125 (45.45%)

70 (38.46%)

 NX

1 (0.22%)

1 (0.36%)

0 (0%)