Table 4 Multivariate analysis of clinical characteristics and CT features for discriminating LC from LM

Age

1.04 (1.01–1.08)

0.009

1.05 (0.99–1.11)

0.102

Smoking

1.83 (1.02–3.30)

0.044

2.81 (0.91–8.64)

0.072

 Colon cancer

2.47 (1.36–4.48)

0.009

1.41 (0.52–3.85)

0.503

 Rectal cancer

Reference

Reference

 Stages I–II

10.75 (5.42–21.33)

< 0.001

21.70 (6.56–71.73)

< 0.001

 Stages III–IV

Reference

Reference

Size of SPN

3.34 (1.92–5.83)

< 0.001

2.01 (0.70–4.80)

0.197

Cranio-caudal location

 Upper

1.48 (0.82–2.66)

0.189

1.33 (0.46–3.79)

0.600

 Non-upper

Reference

Reference

Central

0.50 (0.21–1.17)

0.110

2.11 (0.55–8.14)

0.280

Peripheral

Reference

Reference

 Spiculated margin

36.37 (11.71–112.99)

< 0.001

8.34 (1.39–50.08)

0.020

 Lobulated margin

3.40 (1.39–8.35)

0.007

2.41 (0.66–8.89)

0.186

 Smooth margin

Reference

Reference

 Sub-solid density

62.64 (8.23–476.85)

< 0.001

115.56 (9.96–1341.06)

< 0.001

 Solid density

Reference

Reference

 Yes

13.07 (5.33–32.05)

< 0.001

5.32 (1.15–24.51)

0.032

 No

Reference

Reference

 Yes

1.32 (0.61–2.87)

0.482

 No

Reference

 Yes

5.88 (3.08–11.22)

< 0.001

2.41 (0.77–7.53)

0.131

 No

Reference

Reference

 Yes

1.21 (0.67–2.17)

0.529

 No

Reference

 Yes

3.06 (1.40–6.71)

0.005

1.83 (0.55–6.06)

0.322

 No

Reference

Reference