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Table 1 Comparison of clinicopathological features between early and advanced SMGC patients

From: Clinicopathological features and risk factors analysis of lymph node metastasis and long-term prognosis in patients with synchronous multiple gastric cancer

Factors

Patients (N)

SMGC

P value

Early

Advanced

Gender

0.088#

 Male

45

13

32

 Female

12

7

5

Age (years)

0.121

 < 65

32

14

18

 ≥65

25

6

19

Postoperative hospital stay, median (range, day)

12(9-18)

13(8-55)

0.298

Surgical methods

0.018*#

 B I

11

8

3

 DG + R-Y

9

3

6

 TG + R-Y

37

9

28

BMI, median (range, kg/m2)

21.5 (17.3–26.6)

22.3 (17.6–30.5)

0.2919

Hypertension

1.000#

 Yes

12

4

8

 None

45

16

29

Diabetes

0.607#

 Yes

4

2

2

 None

53

18

35

Number of primary tumors

0.100#

 Two

52

18

34

 Three

3

0

3

 Four

2

2

0

Tumor size

0.012*#

 < 2 cm

4

4

0

 ≥2 cm

53

16

37

Histological type (Adenocarcinoma)a

0.011*#

 Well-differentiated

11

8

3

 Poorly differentiated

46

12

34

Consistency of histology

 

0.174

 Positive

33

14

19

 Negative

24

6

18

Lymph node metastasis

0.002*

 Yes

24

3

21

 None

33

17

16

Ulcer

0.012*#

 Positive

53

16

37

 Negative

4

4

0

Lymphovascular cancer plug

0.111#

 Positive

13

2

11

 Negative

44

18

26

Nerve invasion

0.001*#

 Positive

14

0

14

 Negative

43

20

23

Preoperative CEA, median (range, ng/ml)

2.08 (0.848–4.7)

2.75 (0.2–23.5)

0.0384*

Preoperative CA19-9, median (range, U/ml)

11.035 (0.6–43.2)

10.1 (1.28–173.6)

0.453

Preoperative AFP, median (range, ng/ml)

2.755 (0.947–4.61)

2.66 (1.05–8.25)

0.3063

Preoperative CA153, median (range, U/ml)

7.79 (3.44–20.6)

8.99 (4.9–20.82)

0.7443

Preoperative CA125, median (range, U/ml)

10.91 (5.51–19.51)

11.42 (3.28–39.09)

0.2492

Preoperative CA724, median (range, U/ml)

1.545 (0.2–8.35)

1.95 (0.699–141.1)

0.4754

Operation time, median (range, minute)

158 (90–262)

168 (102–340)

0.6577

Postoperative complication

0.545#

 Yes

3

0

3

 None

54

20

34

Recurrence

0.222#

 Yes

8

1

7

 None

34

14

20

Total

57

20

37

  1. Significant difference existed in several clinicopathological features between early and advanced SMGC patients, including surgical methods, tumor size, histological type, lymph node metastasis, ulcer, nerve invasion, and preoperative CEA
  2. SMGC synchronous multiple gastric cancer, BMI body mass index, B I Billroth I anastomosis, DG distal gastrectomy, TG total gastrectomy, R-Y Roux en-Y anastomosis
  3. *Statistically significant
  4. #Fisher’s exact test