Table 4 Bivariate analysis of MACCE

 Age

1.05

1.02-1.07

< 0.001

 Male sex

0.85

0.50-1.45

0.554

 Ethnicity

0.084

  Chinese

Ref

-

  Malay

0.47

0.17-1.31

0.150

  Indian

1.82

0.63-5.27

0.271

  Others

2.79

0.88-8.82

0.081

 Body mass index (kg/m²)

0.99

0.94-1.04

0.619

 Smoking

1.57

0.78-3.15

0.208

 Hypertension

2.91

1.50-5.62

0.002

 Diabetes mellitus

3.17

1.87-5.37

< 0.001

 Insulin dependent diabetes

4.66

2.18-9.94

<  0.001

 Hyperlipidaemia

2.90

1.60-5.24

< 0001

 Any cardiovascular risk factor

4.30

1.54-12.04

0.005

 Number of cardiovascular risk factor

0.024

  0

Ref

  1

3.20

0.35-29.07

0.302

  2

1.39

0.25-7.60

0.704

  3

4.68

1.65-13.25

0.004

  4

5.12

1.57-16.63

0.007

Charlson co-morbidity index

0.064

 ≤ 3

Ref

 4-6

3.10

1.11-8.66

0.031

 ≥ 7

3.69

1.22-11.16

0.021

 Prior cardiovascular disease

3.55

2.09-6.03

< 0.001

 Peripheral artery disease

3.68

1.57-8.67

0.003

 Chronic kidney disease

4.58

2.03-10.34

< 0.001

Site of cancer

0.714

 Caecal

Ref

 Ascending

1.02

0.32-3.23

0.967

 Transverse

0.41

0.11-1.60

0.200

 Descending

0.41

0.09-1.78

0.234

 Sigmoid

0.70

0.25-1.96

0.493

 Rectosigmoid

0.65

0.18-2.32

0.510

 Rectum

0.68

0.23-2.01

0.486

T stage

0.842

 1

Ref

-

 2

1.07

0.37-3.13

0.900

 3

0.77

0.32-1.82

0.550

 4

0.87

0.34-2.20

0.765

N stage

0.200

 0

Ref

 1

0.62

0.33-1.17

0.137

 2

0.56

0.22-1.40

0.213

M stage

0.21

0.05-0.87

0.032

Stage

0.143

 1

Ref

 2

0.95

0.47-1.92

0.895

 3

0.74

0.35-1.59

0.451

 4

0.19

0.04-0.85

0.030

Grade

0.338

 Low/well-differentiated

Ref

-

 Moderate

0.80

0.33-1.94

0.623

 Poor/high

0.20

0.02-1.69

0.141

Radiotherapy

0.62

0.25-1.55

0.307

Chemotherapy

0.27

0.14-0.51

< 0.001