Table 2 Validation of 7 differentially methylated genes through mixed cohort 1, including breast cancer (GSE141338, GSE100850, GSE117439) and normal (GSE101961)
Gene | Case, N | Control, N | Specificity (%) | Sensitivity (%) | Accuracy (%) |
|---|---|---|---|---|---|
ADCY4 | 81 | 121 | 50.41 | 93.83 | 67.82 |
CPXM1 | 127 | 121 | 85.12 | 95.28 | 90.32 |
DNM3 | 127 | 121 | 59.50 | 89.76 | 75.00 |
GNG4 | 127 | 121 | 98.35 | 84.25 | 91.13 |
MAST1 | 127 | 121 | 81.82 | 97.64 | 89.92 |
PRDM14 | 127 | 121 | 97.52 | 84.25 | 90.73 |
ZNF177 | 127 | 121 | 80.17 | 89.76 | 85.08 |