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Table 2 Anatomical pathology findings in the overall population

From: Atypical parathyroid adenoma: clinical and anatomical pathologic features

  Total population
n = 117
Single gland disease 110 (94.0)
 Typical adenoma 100 (85.5)
 Atypical parathyroid adenoma 10 (8.5)
MGD 7 (6.0)
 Double typical adenoma 7 (6.0)
 Parathyroid hyperplasia 0 (0.0)
Parathyroid carcinoma 0 (0.0)
Size of parathyroid gland (mm)a 24 ± 14
Weight of parathyroid gland (mg) 33 ± 42
Clinical/intraoperative adherence 0 (0.0)
Pseudocapsular Invasion 4 (3.4)
Bands of fibrosis 9 (7.7)
Pronounced trabecular growth 13 (11.1)
Mitotic rates of > 1/10 HPFS 8 (6.8)
Tumor necrosisb 1 (0.9)
Nuclear pleomorphism 4 (3.4)
Cystic degeneration 10 (8.5)
Thick capsule 4 (3.4)
Hemosiderin deposition 5 (4.3)
Hematic extravasion 7 (6.0)
Ki-67+ < 1% 11 (9.4)
Ki-67+ > 4% 4 (3.4)
Galactin-3 + 29 (24.8)
PGP 9.5 + 17 (14.3)
Criteria for malignancyc 0 (0.0)
  1. Data are show as mean ± standard deviation or number (%)
  2. Abbreviations: MGD multiglandular disease, HPFS high-power fields
  3. aMaximum diameter
  4. bNot associated with tumorous infarction or fine-needle aspiration
  5. cInvasion of capsule, vascular, perineural, soft tissue, or surrounding structures (including thyroid, recurrent laryngeal nerve, trachea, esophagus) or documented metastatic disease