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Table 2 Anatomical pathology findings in the overall population

From: Atypical parathyroid adenoma: clinical and anatomical pathologic features

 

Total population

n = 117

Single gland disease

110 (94.0)

 Typical adenoma

100 (85.5)

 Atypical parathyroid adenoma

10 (8.5)

MGD

7 (6.0)

 Double typical adenoma

7 (6.0)

 Parathyroid hyperplasia

0 (0.0)

Parathyroid carcinoma

0 (0.0)

Size of parathyroid gland (mm)a

24 ± 14

Weight of parathyroid gland (mg)

33 ± 42

Clinical/intraoperative adherence

0 (0.0)

Pseudocapsular Invasion

4 (3.4)

Bands of fibrosis

9 (7.7)

Pronounced trabecular growth

13 (11.1)

Mitotic rates of > 1/10 HPFS

8 (6.8)

Tumor necrosisb

1 (0.9)

Nuclear pleomorphism

4 (3.4)

Cystic degeneration

10 (8.5)

Thick capsule

4 (3.4)

Hemosiderin deposition

5 (4.3)

Hematic extravasion

7 (6.0)

Ki-67+ < 1%

11 (9.4)

Ki-67+ > 4%

4 (3.4)

Galactin-3 +

29 (24.8)

PGP 9.5 +

17 (14.3)

Criteria for malignancyc

0 (0.0)

  1. Data are show as mean ± standard deviation or number (%)
  2. Abbreviations: MGD multiglandular disease, HPFS high-power fields
  3. aMaximum diameter
  4. bNot associated with tumorous infarction or fine-needle aspiration
  5. cInvasion of capsule, vascular, perineural, soft tissue, or surrounding structures (including thyroid, recurrent laryngeal nerve, trachea, esophagus) or documented metastatic disease