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Table 4 The univariate and multivariate analysis of various clinic-pathological factors, using overall survival as the dependent variable

From: How does lymph node yield affect survival outcomes of stage I and II colon cancer?

 

Univariate HR

p

*Multivariate HR

p

Age

1.053 (1.041–1.066)

< 0.001

1.059 (1.042–1.076)

< 0.001

Male

1.449 (1.157–1.816)

0.001

1.748 (1.328–2.299)

< 0.001

ASA ≥ 3

2.480 (1.972–3.118)

< 0.001

1.907 (1.443–2.521)

< 0.001

Year of surgery 2003–2007

1.129 (0.894–1.428)

0.308

  

Preoperative CEA

1.004 (1.001–1.006)

0.005

1.005 (1.002–1.008)

< 0.001

CCI

1.364 (1.205–1.543)

< 0.001

  

Obstruction

1.482 (1.133–1.938)

0.004

  

Perforation

2.463 (1.581–3.837)

< 0.001

  

Emergency surgery

1.953 (1.498–2.547)

< 0.001

  

Laparoscopic approach

0.630 (0.502–0.790)

< 0.001

  

Right-sided resection

1.364 (1.094–1.700)

0.006

  

Poor differentiation

1.127 (0.716–1.774)

0.605

  

Tumour size

1.020 (0.908–1.145)

0.741

  

T3/4

1.738 (1.291–2.340)

< 0.001

1.428 (1.022–1.995)

0.037

LVP

1.634 (1.227–2.176)

0.001

1.580 (1.110–2.250)

0.011

Perineural invasion

1.759 (1.185–2.611)

0.005

  

Mucinous

1.124 (0.794–1.925)

0.509

  

LN yield ≥20

0.677 (0.513–0.894)

0.006

  
  1. HR hazard ratio, ASA American Society of Anaesthesiologist grade, CCI Charlson co-morbidity index, CEA carcino-embryonic antigen, LVP lymphovascular permeation
  2. HR > 1 signifies increased likelihood of mortality
  3. *The multivariate analysis only included significant parameters from the univariate analysis