Table 3 The univariate and multivariate analysis of various clinic-pathological factors, using disease-free survival as the dependent variable

Age

1.009 (0.991–1.028)

0.314

Male

1.309 (0.859–1.996)

0.211

ASA ≥ 3

1.150 (0.729–1.815)

0.549

Year of surgery 2003–2007

1.399 (0.919–2.130)

0.117

Preoperative CEA

1.005 (1.002–1.009)

0.001

1.004 (1.000–1.008)

0.038

CCI

0.919 (0.689–1.224)

0.563

Obstruction

2.403 (1.530–3.773)

< 0.001

2.061 (1.128–3.767)

0.019

Perforation

2.971 (1.436–6.145)

0.003

Emergency surgery

2.549 (1.606–4.046)

< 0.001

Laparoscopic approach

0.577 (0.377–0.884)

0.012

Right-sided resection

1.117 (0.739–1.688)

0.601

Poor differentiation

2.902 (1.612–5.223)

< 0.001

2.263 (1.058–4.843)

0.035

Tumour size

1.008 (1.001–1.015)

0.020

T3/4

31.426 (4.378–225.571)

< 0.001

17.216 (2.367–125.235)

0.005

LVP

2.259 (1.385–3.682)

0.001

Perineural invasion

2.713 (1.477–4.983)

0.001

Mucinous

1.777 (1.005–3.143)

0.048

LN yield ≥ 20

0.510 (0.289–0.903)

0.021

0.358 (0.170–0.756)

0.007