Prognostic value of pre-treatment Naples prognostic score (NPS) in patients with osteosarcoma

Table 2 Cut-off values and AUC for NPS and its constituent parameters

Prognostic system	Cut-off value	AUC	Sen (%)	Spe (%)
Albumin (mg/dL)	4	0.664	60.2	74.3
TC (mg/dL)	180	0.690	70.1	65.2
NLR	2.96	0.709	78.3	72.5
LMR	4.44	0.640	90.3	40.6
NPS^a	-	0.766	90.9	86.4

NPS Naples prognostic score, NLR neutrophil-to-lymphocyte ratio, LMR lymphocyte-to-monocyte ratio, AUC area under the curve, Sen sensitivity, Spe specificity
^aNPS is a categorical variable. The cut-off values of these prognostic systems were determined by reference but not by ROC curve analysis. (Gennaro G et. al. 2017, [31])

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