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Table 2 Univariate analysis with newly developed fecal incontinence after total mesorectal excision for rectal cancer

From: Fecal incontinence after total mesorectal excision for rectal cancer—impact of potential risk factors and pelvic intraoperative neuromonitoring

Potential

3 months

 

6 months

 

12 months

 

24 months

 

Risk factors

After SC

p

After SC

p

Post-OP

p

Post-OP

p

Sex

 F

4 of 14

5 of 14

2 of 14

2 of 14

    

 M

6 of 38

0.254

7 of 38

0.172

14 of 38

0.108

15 of 36

0.063

Age (years)

 ≤ 75

8 of 45

9 of 45

12 of 45

13 of 44

    

 > 75

2 of 7

0.406

3 of 7

0.192

4 of 7

0.120

4 of 6

0.093

Tumor site

 Lower rectal third

3 of 16

 

5 of 16

 

9 of 16

 

9 of 16

 

 Middle rectal third

7 of 36

0.636

7 of 36

0.277

7 of 36

0.011*

8 of 34

0.026*

Ant. quadrant involvement

 No

2 of 13

 

3 of 13

 

4 of 13

 

4 of 13

 

 Yes

8 of 39

0.518

9 of 39

0.635

12 of 39

0.627

13 of 37

0.529

Neoadjuvant CRT

 No

8 of 34

 

9 of 34

 

7 of 34

 

8 of 33

 

 Yes

2 of 18

0.244

3 of 18

0.332

9 of 18

0.032*

9 of 17

0.044*

Approach

 Open

10 of 45

 

12 of 45

 

15 of 45

 

15 of 43

 

 Laparoscopic

0 of 7

0.202

0 of 7

0.139

1 of 7

0.295

2 of 7

0.554

Intraoperative blood loss (ml)

 ≤ 1000

8 of 45

 

10 of 45

 

14 of 45

 

15 of 43

 

 > 1000

2 of 7

0.406

2 of 7

0.516

2 of 7

0.633

2 of 7

0.554

pIONM

 Yes

2 of 29

 

3 of 29

 

5 of 29

 

6 of 28

 

 No

8 of 23

0.014*

9 of 23

0.017*

11 of 23

0.019*

11 of 22

0.035*

Mesorectal thickness (cm)*

 < 6

7 of 40

 

7 of 40

 

11 of 40

 

12 of 38

 

 ≥ 6

3 of 12

0.418

5 of 12

0.091

5 of 12

0.277

5 of 12

0.378

Tumor size

 ≤ 4 cm

7 of 35

 

8 of 35

 

11 of 35

 

12 of 33

 

 > 4 cm

3 of 17

0.579

4 of 17

0.608

5 of 17

0.574

5 of 17

0.434

pT-category

 (y)pT 0-2

5 of 27

 

7 of 27

 

10 of 27

 

10 of 26

 

 (y)pT3

5 of 25

0.584

5 of 25

0.431

6 of 25

0.237

7 of 24

0.347

UICC IV

 No

9 of 42

 

11 of 42

 

14 of 42

 

14 of 40

 

 Yes

1 of 10

0.375

1 of 10

0.261

2 of 10

0.341

3 of 10

0.539

Anastomotic leakage

 No

10 of 51

 

12 of 51

 

16 of 51

 

17 of 49

 

 Yes

0 of 1

0.808

0 of 1

0.769

0 of 1

0.692

0 of 1

0.660

  1. SC stoma closure, F female, M male, CRT chemoradiotherapy, pIONM pelvic intraoperative neuromonitoring, UICC Union Internationale Contre le Cancer
  2. *Largest cross-section diameter measured by a pathologist on the fixed specimen. Statistical significance was defined as p < 0.05