Table 2 The list of the differentially expressed genes in the optimized prognostic gene signature was identified by the Cox-proportional hazards (Cox-PH) model
Symbol | Module | Univariate Cox regression analysis | LASSO coefficient | ||
|---|---|---|---|---|---|
HR | 95%CI | P value | |||
ADORA3 | Blue | 1.570 | 1.067–2.549 | 3.40E−02 | 0.44262 |
CPA3 | Blue | 0.810 | 0.679–0.965 | 9.50E−03 | − 0.35894 |
CPM | Green | 0.748 | 0.561–0.995 | 2.30E−02 | − 0.26349 |
EDN3 | Green | 0.830 | 0.670–1.028 | 4.40E−02 | − 0.12557 |
FCRL2 | Blue | 2.465 | 1.298–4.682 | 2.90E−03 | 1.38523 |
MFNG | Blue | 1.456 | 1.127–1.879 | 2.00E−03 | 0.35734 |
NAT1 | Green | 0.514 | 0.368–0.717 | 4.55E−05 | − 0.42755 |
PCSK5 | Green | 1.477 | 1.021–2.138 | 1.95E−02 | 0.30206 |
PPARGC1A | Green | 0.579 | 0.399–0.842 | 2.10E−03 | − 0.34355 |
PRRX2 | Yellow | 1.260 | 1.017–1.559 | 1.70E−02 | 0.04376 |
TNFRSF17 | Blue | 0.780 | 0.597–0.919 | 3.45E−02 | − 0.21594 |
WDR78 | Green | 0.334 | 0.158–0.707 | 2.05E−03 | − 0.07166 |