Table 2 Reported cases in Japan of perforation in the gastrointestinal tract caused by MTX-associated lymphoproliferative disorder
Case | Year | Age | Sex | Organ | CD20 | EBV | Diagnosis | Operation | Chemotherapy | Prognosis |
|---|---|---|---|---|---|---|---|---|---|---|
1 | 1995 | 73 | M | Ileum | Positive | Negative | DLBCL | Rt. hemicolectomy | No | Dead |
2 | 2004 | 87 | F | Ileum | Positive | − | DLBCL | Partial resection | No | Alive |
3 | 2006 | 63 | M | Ileum | Positive | Positive | DLBCL | Ileo-cecum resection | No | Alive |
4 | 2011 | 82 | F | Ileum | Positive | Positive | DLBCL | Ileo-cecum resection | Yesa | Alive |
5 | 2016 | 70 | F | Ileum | Positive | Positive | DLBCL | Rt. hemicolectomy | No | Alive |
6 | 2017 | 77 | F | Ileum | Positive | Negative | DLBCL | Partial resection | No | Alive |
7 | 2018 | 66 | F | Ileum | Positive | Positive | DLBCL | Partial resection | No | Alive |
8 | 2020 | 62 | M | Jejunum | Positive | Positive | DLBCL | Partial resection | No | Alive |
Present case | 2020 | 81 | F | Jejunum | Positive | Positive | EBVMCU | Partial resection | No | Alive |