ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-κB pathway

Table 2 Clinical features of 33 tumor samples

Characteristics	Total of patients	ALKBH2 Low expression (≤ median)	ALKBH2 High expression (> median)	P value
Number	33	17	16
Gender				0.392
Male	21	12	9
Female	12	5	7
Ages (years)				0.325
< 65	22	10	12
≥ 65	11	7	4
Tumor site				0.114
Colon	21	13	8
Rectum	12	4	8
Tumor size(cm)				0.387
< 5	17	10	7
≥ 5	16	7	9
Pathological T category				0.009*
T1-T2	20	13	5
T3-T4	13	4	11
Lymph node metastasis				0.026*
N0	26	16	10
N1-N2	7	1	6
Distant metastasis				0.028*
M0	30	17	12
M1	3	0	4
TNM stage				0.021*
I–II	21	14	7
III–IV	12	3	9
Differentiation				0.353
Well/moderate	20	9	11
Poor	13	8	5

ISSN: 1477-7819