Table 5 The frequency of all grade toxicities in patients with GSTP1 wild type and mutants
| Â | GSTP1 wild type (n = 70) | GSTP1 mutant (n = 34) | ||
|---|---|---|---|---|
Toxicities | G 1–2 | G 3–4 | G 1–2 | G 3–4 |
Hematological toxicity | ||||
 Anemia | 31(29.8) | 14(13.5) | 15(14.4) | 5(4.8) |
 Leucopenia | 35(33.7) | 7(6.7) | 13(12.5) | 3(2.9) |
 Neutropenia | 30(28.8) | 13(12.5) | 9(8.7) | 3(2.9) |
 Thrombocytopenia | 26(25.0) | 8(7.7) | 13(12.5) | 4(3.8) |
Gastrointestinal toxicity | ||||
 Mucositis | 2(1.9) | 7(6.7) | 2(1.9) | 2(1.9) |
 Vomiting | 22(21.2) | 12(11.5) | 5(4.8) | 11(10.6) |
 Diarrhea | 8(7.7) | 7(6.7) | 4(3.8) | 2(1.9) |
Dermatology toxicity | ||||
 Skin ulceration | 5(4.8) | 1(0.9) | 0(0) | 3(2.9) |
 Hand-foot skin reaction | 8(7.7) | 2(1.9) | 3(2.9) | 3(2.9) |