Table 1 Patient demographics and clinical characteristics
Variables | Persistent low group (N = 38) | Persistent high group (N = 21) | Others (N = 43) | p value |
|---|---|---|---|---|
Age, years, mean ± SD | 64.5 ± 8.079 | 65.5 ± 6.875 | 69.2 ± 9.398 | 0.680 |
Male sex, % | 86.8 | 85.7 | 81.4 | 0.904 |
BMI, kg/m2, median | 22.7 (17.4–27.7) | 20.1 (14.1–41.9) | 22.0 (15.0–32.1) | 0.024 |
History of cancer | 0.243 | |||
Yes | 6 | 6 | 12 | |
No | 32 | 15 | 31 | |
History of surgery | 0.193 | |||
Yes | 10 | 9 | 17 | |
No | 28 | 12 | 26 | |
History of alcohol consumption | 0.353 | |||
Yes | 34 | 18 | 39 | |
No | 4 | 3 | 4 | |
History of smoking | 0.953 | |||
Yes | 31 | 17 | 39 | |
No | 7 | 4 | 4 | |
Brinkman index | 632 (0–2700) | 600 (0–2760) | 741 (0–3040) | 0.975 |
< 600 | 0.544 | |||
≥ 600 | 15 | 10 | 19 | |
23 | 11 | 24 | ||
Thoracic approach | 0.234 | |||
VATS | 35 | 17 | 36 | |
Open | 1 | 3 | 5 | |
None: transhiatal | 2 | 1 | 2 | |
Abdominal approach | 0.022 | |||
HALS | 13 | 11 | 23 | |
Open | 6 | 7 | 11 | |
Laparoscopic | 19 | 3 | 9 | |
Lymphadenectomy | 0.247 | |||
D0 | 1 | 2 | 1 | |
D2/3 | 37 (11/26) | 19 (5/14) | 42 (13/29) | |
Curability | 0.665 | |||
R0 | 37 | 20 | 39 | |
R1/2 | 1 | 1 | 4 | |
Reconstruction | 0.780 | |||
Gastric tube | 25 | 12 | 29 | |
Ileocolic | 8 | 6 | 12 | |
Other | 5 | 3 | 2 | |
Thoracic duct | 0.012 | |||
Resected | 16 | 16 | 30 | |
Preserved | 22 | 5 | 13 | |
Reconstruction route | 0.258 | |||
Retrosternal | 30 | 19 | 39 | |
Posterior mediastinal | 8 | 2 | 4 | |
Preoperative treatment | 0.160 | |||
Yes | 16 | 5 | 27 | |
No | 22 | 16 | 16 | |
Operation time (min) | 592 (350–734) | 597 (415–703) | 574 (213–774) | 0.795 |
Blood loss (mL) | 130 (25–1175) | 274 (25–1378) | 260 (38–1094) | 0.067 |
G3 postoperative complications | 0.855 | |||
Yes | 8 | 4 | 11 | |
No | 30 | 17 | 32 | |
cT factor (7th) | 0.303 | |||
1a/1b | 2/16 | 1/5 | 2/10 | |
2 | 12 | 6 | 7 | |
3 | 6 | 6 | 18 | |
4a/4b | 0/2 | 2/1 | 2/4 | |
cN factor (7th) | ||||
0 | 25 | 7 | 13 | 0.029 |
1 | 10 | 11 | 15 | |
2 | 3 | 1 | 15 | |
3 | 0 | 2 | 0 | |
cStage (7th) | 0.109 | |||
I (IA, IB) | 12/9 | 5/0 | 10/2 | |
II (IIA, IIB) | 3/7 | 1/7 | 1/5 | |
III (IIIA, IIIB, IIIC) | 3/1/1 | 1/1/4 | 9/7/5 | |
IV | 2 | 2 | 4 | |
p T factor (7th) | 0.126 | |||
0 | 2 | 2 | 2 | |
1a/1b | 5/19 | 1/6 | 3/8 | |
2 | 8 | 3 | 9 | |
3 | 2 | 6 | 19 | |
4a/4b | 1/1 | 2/1 | 2/0 | |
p N factor (7th) | 0.276 | |||
0 | 26 | 10 | 13 | |
1 | 8 | 8 | 12 | |
2 | 3 | 1 | 11 | |
3 | 1 | 2 | 7 | |
p Stage (7th) | 0.062 | |||
0 | 2 | 1 | 0 | |
I (IA, IB) | 18/2 | 6/0 | 8/3 | |
II (IIA, IIB) | 2/8 | 0/3 | 1/5 | |
III (IIIA, IIIB, IIIC) | 4/0/1 | 3/1/5 | 12/7/5 | |
IV | 1 | 2 | 2 | |
Location of tumor | 0.510 | |||
Cervical Esophagus | 2 | 1 | 1 | |
Upper thoracic esophagus | 5 | 4 | 10 | |
Middle thoracic esophagus | 15 | 12 | 19 | |
Lower thoracic esophagus | 7 | 3 | 10 | |
Abdominal esophagus | 1 | 0 | 0 | |
Esophagogastric junction | 8 | 1 | 3 | |
MAC scale | ||||
Fighting spirit | 51.0 (34–59) | 44.0 (27–57) | 48.0 (29–60) | 0.001 |
Helpless/hopeless | 7.0 (6–16) | 12.0 (6–24) | 10.0 (6–16) | < 0.001 |
Anxious preoccupation | 21.0 (13–29) | 25.0 (17–31) | 23.0 (14–32) | < 0.001 |
Fatalism | 18.0 (8–29) | 21 (12–30) | 22.0 (13–28) | 0.008 |
Avoidance | 1.0 (1–4) | 1.0 (1–4) | 2.0 (1–4) | 0.793 |